Cat: PA2000-4967

Recombinant Human ENAM Protein,His

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关键信息

  • 基因名

    ENAM

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    ENAM;Enamelin

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q9NRM1

  • 表达区间

    1043-1142aa

  • 氨基酸序列

    ERQQQRPSNILHLPCFGSKLAKHHSSTTGTPSSDGRQSPFDGDSITPTENPNTLVELATEEQFKSINVDPLDADEHSPFEFLQRGTNVQDQVQDCLLLQA

  • 分子量

    18.0 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

质检流程

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背景信息

ENAM (enamelin) is a significant structural protein involved in the formation of dental enamel, providing strength and durability to teeth. The research surrounding ENAM is driven by its critical role in amelogenesis (the process of enamel formation) and its influence on dental health. Mutations in the ENAM gene have been linked to various dental disorders, including enamel hypoplasia and other developmental anomalies, which can lead to increased susceptibility to caries and sensitivity. Understanding the biochemical functions and mechanisms of ENAM is crucial, as it not only aids in clarifying the etiologies of enamel defects but also offers potential insights into innovative therapeutic strategies for dental restoration and regenerative approaches. Moreover, harnessing recombinant techniques to produce ENAM allows for in-depth studies on its structural characteristics, interactions with other proteins, and its role in enamel matrix development. Such research is pivotal in enhancing our knowledge of enamel biology, paving the way for advances in dental treatments and preventive measures against enamel-related dental conditions. As we delve deeper into the molecular mechanisms involving ENAM, the potential for translational applications in dentistry continues to expand, highlighting its importance in both health and disease.

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