关键信息
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基因名
MAS1
- 应用
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别名
MAS1; MAS; Proto-oncogene Mas
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P04201
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表达区间
1-325aa
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氨基酸序列
MDGSNVTSFVVEEPTNISTGRNASVGNAHRQIPIVHWVIMSISPVGFVENGILLWFLCFRMRRNPFTVYITHLSIADISLLFCIFILSIDYALDYELSSGHYYTIVTLSVTFLFGYNTGLYLLTAISVERCLSVLYPIWYRCHRPKYQSALVCALLWALSCLVTTMEYVMCIDREEESHSRNDCRAVIIFIAILSFLVFTPLMLVSSTILVVKIRKNTWASHSSKLYIVIMVTIIIFLIFAMPMRLLYLLYYEYWSTFGNLHHISLLFSTINSSANPFIYFFVGSSKKKRFKESLKVVLTRAFKDEMQPRRQKDNCNTVTVETVV
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分子量
63.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
MAS1, or the Mas-related G protein-coupled receptor 1, is a member of the MAS-related gene family, which has gained attention in recent years for its role in various physiological and pathological processes. Initially identified in the context of the cardiovascular system, MAS1 has been implicated in several functions, including regulation of blood pressure, modulation of inflammatory responses, and influence on pain perception. Its activation is thought to participate in neuroprotective pathways and may contribute to the resolution of inflammation. The recombinant expression of MAS1 protein has been a focus of research to elucidate its signaling mechanisms and potential therapeutic applications. Characterizing MAS1 as a recombinant protein enables scientists to conduct in-depth investigations into its ligand-binding properties, signaling pathways, and interactions with other cellular components. Understanding the structure-function relationships of MAS1 can provide insights into its role in diseases such as hypertension, pain disorders, and cancer. Given the growing interest in GPCRs as drug targets, research involving MAS1 recombinant protein may pave the way for novel therapeutic strategies aimed at modulating its activity for clinical benefit. Overall, the study of MAS1 and its recombinant forms presents significant opportunities for advancing our understanding of GPCR biology and developing innovative treatments for various ailments.
