关键信息
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基因名
FOXL2
- 应用
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别名
FOXL2；Forkhead box Protein L2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P58012
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表达区间
1-376aa
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氨基酸序列
MMASYPEPEDAAGALLAPETGRTVKEPEGPPPSPGKGGGGGGGTAPEKPDPAQKPPYSYVALIAMAIRESAEKRLTLSGIYQYIIAKFPFYEKNKKGWQNSIRHNLSLNECFIKVPREGGGERKGNYWTLDPACEDMFEKGNYRRRRRMKRPFRPPPAHFQPGKGLFGAGGAAGGCGVAGAGADGYGYLAPPKYLQSGFLNNSWPLPQPPSPMPYASCQMAAAAAAAAAAAAAAGPGSPGAAAVVKGLAGPAASYGPYTRVQSMALPPGVVNSYNGLGGPPAAPPPPPHPHPHPHAHHLHAAAAPPPAPPHHGAAAPPPGQLSPASPATAAPPAPAPTSAPGLQFACARQPELAMMHCSYWDHDSKTGALHSRLDL
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分子量
43.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
FOXL2 (Forkhead Box L2) is a pivotal transcription factor crucial for the development and function of ovarian tissues in vertebrates. Identified as a key player in ovarian differentiation, FOXL2 is involved in maintaining the identity and function of ovarian somatic cells, and it plays a significant role in sex determination and reproductive health. Mutations or dysregulation of FOXL2 have been linked to various reproductive disorders, including premature ovarian insufficiency (POI) and certain forms of granulosa cell tumors. Research on FOXL2 recombinant proteins aims to elucidate its functional domains, interaction partners, and regulatory mechanisms, providing insights into its role in ovarian biology and related pathologies. The production of FOXL2 recombinant proteins allows for detailed biochemical and structural analyses, facilitating the exploration of its transcriptional regulation and signaling pathways. Furthermore, the study of FOXL2's molecular interactions can inform potential therapeutic strategies targeting ovarian dysfunctions. As such, understanding FOXL2 at the protein level is critically important for advancing reproductive health research and developing novel treatments for ovarian diseases.
