关键信息
-
基因名
CH1
- 应用
-
别名
CH1；C1orf9；CH1；OPT；SUN domain-containing ossification factor
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
P30438
-
表达区间
23-92aa
-
氨基酸序列
EICPAVKRDVDLFLTGTPDEYVEQVAQYKALPVVLENARILKNCVDAKMTEEDKENALSVLDKIYTSPLC
-
分子量
15.3 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CH1 recombinant protein, derived from the CH1 domain of antibody light chains, plays a significant role in various biotechnological and therapeutic applications. The CH1 domain is crucial for the stability and functionality of antibodies, which are essential tools in medicine, diagnostics, and research. With the growing need for humanized antibodies in the treatment of diseases such as cancer and autoimmune disorders, the development and production of CH1 recombinant proteins have become increasingly important. These proteins facilitate the engineering of novel antibody formats, improve the yield and stability of antibody production, and enhance the efficacy of therapeutic antibodies. By utilizing recombinant DNA technology, CH1 proteins can be expressed in multiple systems, including bacteria, yeast, and mammalian cells, allowing for scalable production and fine-tuning of their properties. The study of CH1 recombinant proteins also aids in understanding the structure-function relationships within antibodies, enabling the design of more effective biopharmaceuticals. As research in this area continues to evolve, CH1 recombinant proteins are expected to play a pivotal role in advancing antibody therapeutics and improving patient outcomes.
