关键信息
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基因名
RCN1
- 应用
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别名
RCN1;RCN;Reticulocalbin-1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15293
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表达区间
30-331aa
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氨基酸序列
MRGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSELEKPTVRKERVVR PDSELGERPPEDNQSFQYDHEAFLGKEDSKTFDQLTPDESKERLGKIVDR IDNDGDGFVTTEELKTWIKRVQKRYIFDNVAKVWKDYDRDKDDKISWEEY KQATYGYYLGNPAEFHDSSDHHTFKKMLPRDERRFKAADLNGDLTATREE FTAFLHPEEFEHMKEIVVLETLEDIDKNGDGFVDQDEYIADMFSHEENGP EPDWVLSEREQFNEFRDLNKDGKLDKDEIRHWILPQDYDHAQAEARHLVY ESDKNKDEKLTKEEILENWNMFVGSQATNYGEDLTKNHDEL
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分子量
40 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
Recombinant RCN1 (Regulator of Calcium and Nucleotides 1) protein has garnered substantial attention in recent years due to its critical role in cellular calcium signaling and its involvement in various physiological and pathological processes. RCN1 functions as a calcium-binding protein that regulates the activity of several target proteins, influencing cellular responses to calcium fluctuations. Research has suggested that RCN1 is implicated in numerous diseases, including neurodegenerative disorders, cancer, and cardiovascular diseases, making it a potential therapeutic target. The ability to produce RCN1 as a recombinant protein allows researchers to study its structure, function, and interactions with other cellular components in detail. By understanding the molecular mechanisms underlying RCN1's activity, scientists aim to develop novel strategies for disease intervention and therapeutic applications. Furthermore, the exploration of RCN1's role in calcium homeostasis sheds light on fundamental cellular processes, potentially leading to advancements in biotechnology and drug development. As research continues, the recombinant expression and purification of RCN1 are expected to provide deeper insights into its biological significance and pave the way for innovative approaches in medical science.
