关键信息
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基因名
RCVRN
- 应用
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别名
RCVRN;RCV1;Recoverin
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P35243
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表达区间
1-200aa
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氨基酸序列
MGNSKSGALS KEILEELQLN TKFSEEELCS WYQSFLKDCP TGRITQQQFQ SIYAKFFPDT DPKAYAQHVF RSFDSNLDGT LDFKEYVIAL HMTTAGKTNQ KLEWAFSLYD VDGNGTISKN EVLEIVMAIF KMITPEDVKL LPDDENTPEK RAEKIWKYFG KNDDDKLTEK EFIEGTLANK EILRLIQFEP QKVKEKMKNA
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分子量
23 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
RCVRN (Retinal Cone-specific Vision-related Protein) is a crucial protein implicated in the maintenance and function of photoreceptor cells, particularly in the retina where it plays a vital role in vision. Research on RCVRN has gained prominence due to its potential association with various retinal degenerative diseases, such as retinitis pigmentosa and age-related macular degeneration. Understanding the structure and function of RCVRN is essential for unraveling the molecular mechanisms underlying these conditions and for developing therapeutic strategies. Studies have shown that RCVRN is specifically expressed in cone photoreceptors, highlighting its significance in color vision. Additionally, the exploration of RCVRN as a target for gene therapy and regenerative medicine offers promising avenues for restoring vision in affected individuals. As scientists delve deeper into the biochemical pathways involving RCVRN, significant insights into the pathology of retinal diseases are anticipated, paving the way for innovative approaches in ocular therapeutics. Enhanced knowledge of RCVRN's role could thus not only contribute to basic science but can also impact clinical strategies aimed at combating vision loss.
