Recombinant Human C11orf80 Protein

C11orf80 (Chromosome 11 Open Reading Frame 80) is a poorly characterized human protein encoded by the C11orf80 gene located on chromosome 11q13.1. Currently classified as a "hypothetical protein," its biological function, structure, and cellular role remain largely unstudied. Bioinformatics analyses suggest it may contain conserved regions indicative of potential enzymatic or regulatory domains, though experimental validation is lacking. Transcriptomic data from public databases (e.g., GTEx) indicate low to moderate expression across human tissues, with slightly elevated levels in brain, testis, and muscle. Some proteomic studies detect C11orf80 in nuclear and cytoplasmic compartments, hinting at possible involvement in basic cellular processes. A few high-throughput interaction screens tentatively link it to RNA-binding proteins and chromatin modifiers, but these associations require confirmation. No direct disease connections have been established, though its genomic neighborhood near cancer-associated loci (e.g., CCND1) raises unanswered questions about potential roles in oncogenesis. The lack of specific antibodies, knockout models, and structural data (no solved 3D structures exist) significantly hinders functional characterization. Current understanding remains limited to computational predictions, urging systematic investigation into its molecular interactions, post-translational modifications, and physiological context. Its alternative designation as PRO1837 or FLJ32710 appears sporadically in older literature.