关键信息
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基因名
NRIP1
- 应用
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别名
NRIP 1; NRIP1; NRIP1_HUMAN; Nuclear factor RIP 140; Nuclear factor RIP140; Nuclear receptor interacting protein 1; Nuclear receptor-interacting protein 1; Receptor interacting protein 140; Receptor-interacting protein 140; RIP 140; RIP140
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P48552
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表达区间
1051-1158 aa
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氨基酸序列
KNEYEKDSPRLTKTNPILYYMLQKGGNSVTSRETQDKDIWREASSAESVSQVTAKEELLPTAETKASFFNLRSPYNSHMGNNASRPHSANGEVYGLLGSVLTIKKESE
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分子量
37.62 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
NRIP1, also known as Nuclear Receptor Interacting Protein 1, is a co-regulator that plays a crucial role in the regulation of various nuclear receptors and gene expression. Its involvement in multiple biological processes, including metabolism, immune response, and cell differentiation, has garnered significant interest in the scientific community. Dysregulation of NRIP1 has been implicated in various diseases, including cancer and metabolic disorders, highlighting its potential as a therapeutic target. Research on NRIP1 often focuses on its molecular interactions and functions, aiming to elucidate the mechanisms through which it influences gene transcription and cellular signaling pathways. The use of recombinant protein technology to produce NRIP1 allows for detailed structural and functional studies, facilitating insights into its role in health and disease. Furthermore, understanding the dynamics of NRIP1's interactions with other proteins and nuclear receptors can lead to the identification of novel drug targets and therapeutic strategies. Overall, NRIP1 continues to be a prominent subject of research, with the potential to contribute significantly to our understanding of gene regulation and disease pathology.
