关键信息
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基因名
ABHD14A
- 应用
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别名
ABHD14A; UNQ1913/PRO4373; Protein ABHD14A
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9BUJ0
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表达区间
1-271aa
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氨基酸序列
MVGALCGCWFRLGGARPLIPLGPTVVQTSMSRSQVALLGLSLLLMLLLYVGLPGPPEQTSCLWGDPNVTVLAGLTPGNSPIFYREVLPLNQAHRVEVVLLHGKAFNSHTWEQLGTLQLLSQRGYRAVALDLPGFGNSAPSKEASTEAGRAALLERALRDLEVQNAVLVSPSLSGHYALPFLMRGHHQLHGFVPIAPTSTQNYTQEQFWAVKTPTLILYGELDHILARESLRQLRHLPNHSVVKLRNAGHACYLHKPQDFHLVLLAFLDHLP
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分子量
29.7 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
ABHD14A, a member of the serine hydrolase family, has gained significant attention in recent years due to its potential role in lipid metabolism and cellular signaling pathways. It is predominantly expressed in the brain and has been implicated in various physiological processes, including neurotransmitter regulation and the maintenance of neuronal integrity. Research indicates that ABHD14A may be involved in the hydrolysis of endocannabinoids, which are crucial for modulating synaptic transmission and neuroplasticity. Dysregulation of ABHD14A has been associated with several neurological disorders, making it a potential target for therapeutic interventions. The production of recombinant ABHD14A protein enables detailed structural and functional studies, facilitating the elucidation of its enzymatic mechanisms and interactions with lipid substrates. Understanding the biochemical properties and biological functions of ABHD14A could provide valuable insights into its role in health and disease, paving the way for novel treatment strategies in neurodegenerative and psychiatric disorders.
