关键信息
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基因名
OPN1SW
- 应用
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别名
OPN1SW; BCP; Short-wave-sensitive opsin 1; Blue cone photoreceptor pigment; Blue-sensitive opsin; BOP
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P03999
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氨基酸序列
MRKMSEEEFYLFKNISSVGPWDGPQYHIAPVWAFYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGFLLCIFSVFPVFVASCNGYFVFGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVICKPFGNFRFSSKHALTVVLATWTIGIGVSIPPFFGWSRFIPEGLQCSCGPDWYTVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQLLRALKAVAAQQQESATTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVNNRNHGLDLRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIMKMVCGKAMTDESDTCSSQKTEVSTVSSTQVGPN
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分子量
38.28 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
OPN1SW, also known as the short-wavelength sensitive opsin, is a crucial photoreceptor protein found in the human retina, primarily expressed in cone cells responsible for color vision. This protein is involved in the perception of blue light, playing a vital role in our visual system. Mutations or variations in the OPN1SW gene can lead to color vision deficiencies or retinopathies, significantly impacting individuals’ quality of life. Research into OPN1SW has gained momentum due to its implications for understanding the molecular mechanisms of color vision, as well as its potential applications in gene therapy and retinal regenerative medicine. Scientists utilize recombinant DNA technology to produce OPN1SW protein for structural and functional studies, allowing for a deeper exploration of its properties and interactions with other retinal proteins. Investigating OPN1SW not only enhances our knowledge of normal vision processes but also contributes to identifying therapeutic targets for vision disorders caused by congenital or acquired defects in phototransduction. Insights gained from OPN1SW research may pave the way for innovative strategies to restore or enhance vision, highlighting the significance of this protein in both basic and applied biomedical research.
