关键信息
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基因名
Sp17
- 应用
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别名
SPA17;SP17;Sperm surface Protein Sp17
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15506
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表达区间
1-146aa
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氨基酸序列
MSIPFSNTHYRIPQGFGNLLEGLTREILREQPDNIPAFAAAYFESLLEKREKTNFDPAEWGSKVEDRFYNNHAFEEQEPPEKSDPKQEESQISGKEEETSVTILDSSEEDKEKEEVAAVKIQAAFRGHIAREEAKKMKTNSLQNEE
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分子量
43.8kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
The study of Sp17 recombinant protein is rooted in the field of reproductive immunology and infertility research. Sp17 is a sperm-specific protein that plays a crucial role in sperm function and fertilization processes. It is encoded by a gene that is expressed primarily in the male reproductive system and is thought to be involved in the interaction between sperm and the female reproductive tract. The characterization of Sp17 has gained interest due to its potential as a biomarker for male fertility assessment and its implications in the development of immunocontraceptive methods. Investigations into the structure, function, and immunogenicity of Sp17 can provide insights into the mechanisms governing sperm-egg interactions, as well as the underlying causes of male infertility. Additionally, the production of Sp17 as a recombinant protein opens avenues for both diagnostic and therapeutic applications, including the development of targeted fertility treatments and contraceptive vaccines. The growing understanding of Sp17's role in reproduction emphasizes the importance of this protein in reproductive health research and its potential to influence strategies for addressing infertility issues.
