关键信息
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基因名
SRA1
- 应用
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别名
SRA1;Steroid receptor RNA activator 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9HD15
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表达区间
90-236aa
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氨基酸序列
MGSSHHHHHH SSGLVPRGSH MGSVGSGPAS GVEPTSFPVE SEAVMEDVLR PLEQALEDCR GHTRKQVCDD ISRRLALLQE QWAGGKLSIP VKKRMALLVQ ELSSHRWDAA DDIHRSLMVD HVTEVSQWMV GVKRLIAEKR SLFSEEAANE EKSAATAEKN HTIPGFQQAS
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分子量
19 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
SRA1 (Steroid Receptor RNA Activator 1) is a novel protein with significant implications in gene regulation, particularly in the context of steroid receptor signaling. Research into SRA1 has gained traction due to its role as a coactivator for various nuclear hormone receptors, influencing the transcription of target genes involved in crucial physiological processes such as metabolism, development, and immune response. Its unique characteristic of being a long non-coding RNA suggests that SRA1 might function through diverse mechanisms, including RNA-protein interactions and chromatin remodeling. The exploration of SRA1's functions extends into its potential involvement in pathological conditions, including cancer, where dysregulation of steroid receptor signaling is often observed. Investigations into SRA1's structure and functional domains are necessary to fully elucidate its role in cellular processes and its interactions with other molecular players in steroid hormone signaling pathways. As the understanding of SRA1 evolves, it could pave the way for new therapeutic strategies targeting diseases linked to hormone receptor dysregulation. Overall, the study of SRA1 represents a burgeoning field that bridges molecular biology and medical research, highlighting the complexities of non-coding RNA molecules in gene expression regulation.
