关键信息
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基因名
OXA1L
- 应用
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别名
OXA1L; Mitochondrial inner membrane protein OXA1L; Hsa; OXA1Hs; Oxidase assembly 1-like protein; OXA1-like protein
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15070
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表达区间
1-113 aa
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氨基酸序列
MAMGLMCGRRELLRLLQSGRRVHSVAGPSQWLGKPLTTRLLFPVAPCCCRPHYLFLAASG PRSLSTSAISFAEVQVQAPPVVAATPSPTAVPEVASGETADVVQTAAEQSFAE
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分子量
48.5 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
OXA1L, or Oxa1-like protein, is a crucial component of mitochondrial protein synthesis, playing a significant role in the insertion of peptides into the inner mitochondrial membrane. It is involved in the biogenesis and maintenance of the mitochondrial respiratory chain complexes, which are essential for ATP production through oxidative phosphorylation. Mutations or dysfunctions in OXA1L have been associated with various mitochondrial diseases, highlighting its importance in cellular energy metabolism and human health. Research on OXA1L recombinant proteins has gained traction as scientists aim to elucidate its structural and functional properties. Studying these recombinant proteins can provide insights into the mechanisms of mitochondrial translation and assembly, potentially leading to therapeutic strategies for mitochondrial disorders. Furthermore, understanding OXA1L's interactions with other mitochondrial factors may reveal intricate regulatory networks within the mitochondria, contributing to a broader knowledge of mitochondrial dynamics and their implications in aging and neurodegenerative diseases. The exploration of OXA1L recombinant protein not only enhances our fundamental understanding of mitochondrial biology but also offers a promising avenue for developing novel interventions to combat related diseases.
