Recombinant Human FLJ23356 Protein

Recombinant human FLJ23356 protein is derived from the FLJ23356 gene, a poorly characterized human gene initially identified through large-scale cDNA sequencing projects. The FLJ23356 gene, also designated as a "hypothetical protein" in early genomic databases, encodes a protein with unknown molecular function, though bioinformatic analyses suggest potential roles in intracellular signaling or regulatory pathways. Its amino acid sequence contains conserved domains indicative of protein-protein interaction capabilities, including a putative transmembrane region and coiled-coil motifs, implying possible localization to cellular membranes or involvement in structural organization.

Recombinant FLJ23356 is typically produced using heterologous expression systems, such as *E. coli* or mammalian cell cultures (e.g., HEK293), enabling functional studies and antibody production. Despite limited literature, transcriptomic data show variable FLJ23356 expression across tissues, with higher levels observed in brain and reproductive organs, hinting at tissue-specific functions. Some proteomic studies have detected FLJ23356 in exosome fractions, suggesting extracellular communication roles. Current research focuses on elucidating its interaction partners via affinity purification-mass spectrometry and mapping its involvement in diseases through gene knockout models. However, its precise biological significance remains enigmatic, positioning recombinant FLJ23356 as a tool for exploratory studies in cell biology and disease mechanisms, particularly in cancers and neurological disorders where differential expression has been preliminarily reported.