| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | FLJ39743 |
| Uniprot No | 0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-192aa |
| 氨基酸序列 | MKVQSFGERVVLFILNAIIFGRLERNLDDDDMFFLPHSVKEQAKILWRRGAAVGFYTTKMKGRLCGDGTGACYLLPVFDTVFIRRKHWHRGLGTAMLRDFCETFPEDEALGVSCSMSPAMYQAHPGNSEDVSRHARTSQNDRPRQPAPGDGSKERMCGEELEDTKDDPECGVEEEDAGLAGQPPGKLTRSSP |
| 分子量 | 48.07 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
关于重组人FLJ39743蛋白的研究目前公开文献较少，该基因编号可能对应已被重新命名或尚未深入研究的功能未知蛋白。以下是假设性示例(非真实文献，仅供参考)：
1. **文献名称**："Expression and Functional Analysis of Recombinant Human FLJ39743 Protein in Cancer Cell Lines"
**作者**：Chen X, et al.
**摘要**：研究成功在大肠杆菌中表达并纯化了重组人FLJ39743蛋白，发现其在乳腺癌细胞中通过调控EGFR信号通路抑制细胞迁移。
2. **文献名称**："Structural Characterization of FLJ39743 and Its Interaction with Ubiquitin Ligases"
**作者**：Yamamoto K, et al.
**摘要**：通过X射线晶体学解析了FLJ39743的三维结构，证实其与E3泛素连接酶的相互作用可能参与蛋白质降解调控。
3. **文献名称**："FLJ39743 as a Potential Biomarker in Liver Fibrosis"
**作者**：Guo L, et al.
**摘要**：发现血清中FLJ39743水平与肝纤维化程度正相关，重组蛋白的体外实验显示其可激活肝星状细胞的促纤维化通路。
**注意事项**：
- 目前数据库中FLJ39743的正式名称可能已被更新(如C1orf123等)，建议通过UniProt或NCBI Gene确认最新基因符号。
- 实际文献检索建议使用PubMed/Google Scholar，结合基因别名及功能关键词(如“uncharacterized protein”、“cancer”等)。
Recombinant human FLJ39743 protein is a genetically engineered protein derived from the FLJ39743 gene, which encodes a protein of unknown function that remains poorly characterized in current scientific literature. The gene, also identified by its genomic locus or alternative accession numbers, is conserved across species, suggesting potential biological significance. Structurally, FLJ39743 is predicted to contain functional domains indicative of enzymatic or regulatory roles, though experimental validation is limited. Its expression profile, inferred from transcriptomic data, shows tissue-specific patterns, with higher activity in certain organs, but its physiological relevance remains unclear.
The production of recombinant FLJ39743 typically involves expression systems such as E. coli or mammalian cell cultures, followed by purification using affinity chromatography. This enables functional studies to explore its interactions, post-translational modifications, and potential involvement in cellular pathways. Interest in this protein stems from its association with disease contexts, including cancer or metabolic disorders, hinted by differential expression in pathological versus normal tissues. However, mechanistic insights are lacking, necessitating further research to elucidate its role in health and disease.
Current applications focus on using recombinant FLJ39743 as a reagent in antibody development, protein interaction assays, or as an antigen for biomarker discovery. Despite its enigmatic nature, ongoing efforts in proteomics and structural biology aim to unravel its molecular functions, which could unlock therapeutic or diagnostic opportunities. The lack of comprehensive studies underscores both the challenges and potential of FLJ39743 as a subject for future biomedical exploration.
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