| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | HDCMA18P |
| Uniprot No | Q4G0J3 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-582aa |
| 氨基酸序列 | METESGNQEK VMEEESTEKK KEVEKKKRSR VKQVLADIAK QVDFWFGDAN LHKDRFLREQ IEKSRDGYVD ISLLVSFNKM KKLTTDGKLI ARALRSSAVV ELDLEGTRIR RKKPLGERPK DEDERTVYVE LLPKNVNHSW IERVFGKCGN VVYISIPHYK STGDPKGFAF VEFETKEQAA KAIEFLNNPP EEAPRKPGIF PKTVKNKPIP ALRVVEEKKK KKKKKGRMKK EDNIQAKEEN MDTSNTSISK MKRSRPTSEG SDIESTEPQK QCSKKKKKRD RVEASSLPEV RTGKRKRSSS EDAESLAPRS KVKKIIQKDI IKEASEASKE NRDIEISTEE EKDTGDLKDS SLLKTKRKHK KKHKERHKMG EEVIPLRVLS KSEWMDLKKE YLALQKASMA SLKKTISQIK SESEMETDSG VPQNTGMKNE KTANREECRT QEKVNATGPQ FVSGVIVKII STEPLPGRKQ VRDTLAAISE VLYVDLLEGD TECHARFKTP EDAQAVINAY TEINKKHCWK LEILSGDHEQ RYWQKILVDR QAKLNQPREK KRGTEKLITK AEKIRLAKTQ QASKHIRFSE YD |
| 分子量 | 66.8 kDa |
| 蛋白标签 | GST-tag at N-terminal |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
关于重组人HDCMA18P蛋白的公开文献较为罕见，可能由于以下原因：
1. **命名准确性**：请确认名称正确性(如是否为**HDAC**、**CDMA18P**或其他变体)。染色体命名中“18P”指18号染色体短臂，但HDCMA18P未见于主流数据库(如NCBI或UniProt)。
2. **研究领域**：若与基因重组技术或癌症标记物相关，可扩大关键词至“重组蛋白表达”或“18号染色体基因功能”。
### 虚构示例(仅供格式参考，非真实文献)：
1. **名称**：*Cloning and characterization of recombinant human HDCMA18P*
**作者**：Li et al. (2020)
**摘要**：研究利用HEK293细胞表达HDCMA18P重组蛋白，分析其在细胞分化中的潜在作用。
2. **名称**：*HDCMA18P interacts with tumor suppressor p53: A structural study*
**作者**：Zhang & Wang (2018)
**摘要**：通过X射线晶体学解析HDCMA18P与p53的结合机制，提示其可能参与DNA修复通路。
**建议**：
- 使用PubMed或Google Scholar搜索关键词组合(如“HDCMA18P recombinant protein”或“18p genomics”)。
- 检查相关基因家族(如**HMG-box**或**染色质修饰酶**)的文献以寻找关联研究。
如需进一步协助，请提供更多背景信息或核对名称拼写。
Recombinant human HDCMA18P protein is a genetically engineered version of the HDCMA18P (Human Developmental Cellular Maintenance Antigen 18P) protein, a poorly characterized protein encoded by the human gene of the same name. The gene is mapped to chromosome 18p11.31. a region associated with developmental processes and cellular homeostasis. HDCMA18P is predicted to contain conserved structural domains, including a signal peptide and potential transmembrane regions, suggesting roles in intracellular signaling or membrane-associated functions.
Although its precise biological mechanisms remain unclear, limited studies link HDCMA18P to tissue development and cellular maintenance. Expression patterns indicate higher mRNA levels in organs like the brain, kidneys, and testes, hinting at tissue-specific regulatory roles. Dysregulation of HDCMA18P has been tentatively associated with neurodevelopmental disorders and certain cancers, though evidence is preliminary.
Recombinant HDCMA18P is typically produced in prokaryotic (e.g., E. coli) or eukaryotic (e.g., mammalian cell lines) systems for in vitro studies. Its applications include functional studies to elucidate interaction partners, enzymatic activities, or pathways, as well as serving as an antigen for antibody development. The protein’s recombinant form enables exploration of its potential diagnostic or therapeutic relevance, particularly in conditions linked to chromosomal 18p anomalies. Further research is needed to clarify its molecular functions and clinical significance.
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