关键信息
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基因名
IL20RB
- 应用
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别名
IL20RB；DIRS1；Interleukin-20 receptor subunit beta
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q6UXL0
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表达区间
30-230aa
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氨基酸序列
DEVAILPAPQNLSVLSTNMKHLLMWSPVIAPGETVYYSVEYQGEYESLYT SHIWIPSSWCSLTEGPECDVTDDITATVPYNLRVRATLGSQTSAWSILKH PFNRNSTILTRPGMEITKDGFHLVIELEDLGPQFEFLVAYWRREPGAEEH VKMVRSGGIPVHLETMEPGAAYCVKAQTFVKAIGRYSAFSQTECVEVQGE AVDDIEGRMDEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISR TPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSV LTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSR EEMTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFF LYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
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分子量
50 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
IL20RB (Interleukin 20 receptor beta) is a crucial component of the cytokine signaling pathway that regulates various immune responses and inflammatory processes. Research has increasingly focused on IL20RB due to its role in mediating the effects of interleukin-20 (IL-20) and interleukin-24 (IL-24), both of which are implicated in skin conditions like psoriasis and other autoimmune disorders. IL20RB forms a receptor complex with IL20RA, and their interaction is essential for transducing signals that contribute to the differentiation and proliferation of immune cells. Understanding the structure and function of IL20RB, particularly through recombinant protein studies, can provide insights into its role in disease mechanisms. Furthermore, as a target for therapeutic intervention, IL20RB presents opportunities for the development of novel biologics aimed at modulating immune responses. Recombinant IL20RB can be utilized in various assays to explore its interactions with other cytokines and receptors, as well as to identify potential inhibitors or agonists. This research is vital not only for elucidating the basic biology of cytokine signaling but also for the potential advancement of treatments for inflammatory diseases that involve the IL-20 signaling pathway.
