关键信息
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基因名
PF4
- 应用
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别名
PF4；CXCL4V1；SCYB4V1；Platelet factor 4 variant
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
P02776
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表达区间
31-101aa
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氨基酸序列
EAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY KKIIKKLLES
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分子量
8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
PF4 (Platelet Factor 4) is a chemokine primarily produced by platelets and plays a pivotal role in hemostasis, inflammation, and tissue repair. Its involvement in various physiological and pathological processes has spurred significant interest in PF4 as a molecular target for therapeutic interventions. Research has revealed that PF4 is not only crucial in modulating immune responses but also in mediating angiogenesis and wound healing. Furthermore, it has been implicated in conditions such as thrombosis, atherosclerosis, and even cancer, indicating its importance in disease progression. The study of recombinant PF4 proteins has provided insights into their structure-function relationships, allowing researchers to explore its mechanisms of action in detail. Advances in recombinant DNA technology have enabled the production of PF4 variants, which can be used to investigate their biological properties, develop new diagnostic tools, and create potential therapeutic agents. Additionally, the role of PF4 in vaccine responses and as a biomarker in various diseases is an emerging area of interest, highlighting its potential utility in clinical settings. Thus, exploring the properties and applications of recombinant PF4 is essential for advancing our understanding of its biological significance and therapeutic potential.
