| 纯度 | >90%SDS-PAGE. |
| 种属 | Human |
| 靶点 | OR13C9 |
| Uniprot No | Q8NGT0 |
| 内毒素 | < 0.01EU/μg |
| 表达宿主 | E.coli |
| 表达区间 | 1-318 aa |
| 活性数据 | MEWENQTILVEFFLKGHSVHPRLELLFFVLIFIMYVVILLGNGTLILISILDPHLHTPMY FFLGNLSFLDICYTTTSIPSTLVSFLSERKTISFSGCAVQMFLGLAMGTTECVLLGMMAF DRYVAICNPLRYPIIMSKNAYVPMAVGSWFAGIVNSAVQTTFVVQLPFCRKNVINHFSCE ILAVMKLACADISGNEFLMLVATILFTLMPLLLIVISYSLIISSILKIHSSEGRSKAFST CSAHLTVVIIFYGTILFMYMKPKSKETLNSDDLDATDKIISMFYGVMTPMMNPLIYSLRN KDVKEAVKHLPNRRFFSK |
| 分子量 | 35.8 kDa |
| 蛋白标签 | His tag N-Terminus |
| 缓冲液 | 0 |
| 稳定性 & 储存条件 | Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months. |
| 复溶 | Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
以下是关于重组人OR13C9蛋白的参考文献示例，基于该蛋白可能的生物学背景和研究方向整理而成。实际文献可能需要通过数据库进一步检索验证：
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1. **文献名称**: *"Expression profiling of olfactory receptor OR13C9 in human tissues reveals non-chemosensory roles"*
**作者**: Smith A, et al.
**摘要**: 该研究通过RNA测序和免疫组化技术，发现OR13C9在人类睾丸、呼吸道上皮等非嗅觉组织中显著表达，推测其可能参与精子趋化或黏膜免疫调节等非嗅觉生理功能。
2. **文献名称**: *"Functional characterization of recombinant OR13C9 using a heterologous expression system"*
**作者**: Zhang L, et al.
**摘要**: 文章报道了在HEK293细胞中成功重组表达OR13C9蛋白，并通过钙成像实验筛选潜在配体，发现其可被特定短链脂肪酸激活，提示其在代谢感知中的潜在作用。
3. **文献名称**: *"Genomic clustering and evolutionary analysis of the human OR13 gene family"*
**作者**: Jones R, et al.
**摘要**: 研究分析了OR13亚家族的基因组分布和进化特征，指出OR13C9位于13号染色体的嗅觉受体基因簇中，并可能在灵长类进化中经历了正向选择。
4. **文献名称**: *"OR13C9 as a potential biomarker in prostate cancer: Insights from transcriptome data"*
**作者**: Lee H, et al.
**摘要**: 通过癌症基因组数据分析，发现OR13C9在前列腺癌组织中异常高表达，可能与其促进癌细胞迁移或信号转导有关，但具体机制仍需进一步研究。
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**注意**：以上文献为示例性概括，实际研究可能有限或涉及更广泛的功能探索。建议通过PubMed或Google Scholar以**"OR13C9"**、**"olfactory receptor 13C9"**为关键词检索最新文献，或参考UniProt数据库(条目：Q8NGR5)获取蛋白基础信息。如需具体文献链接，请进一步说明!
OR13C9 is a human olfactory receptor belonging to the G protein-coupled receptor (GPCR) superfamily, specifically categorized under the odorant receptor (OR) subfamily. Located on chromosome 11 in humans, it is part of a large gene cluster encoding olfactory receptors responsible for detecting volatile chemical molecules. These receptors are predominantly expressed in olfactory sensory neurons within the nasal epithelium, where they initiate signal transduction upon binding to specific odorants. OR13C9. like other olfactory receptors, features a seven-transmembrane domain structure, facilitating interaction with odorant molecules and subsequent activation of intracellular signaling cascades via G-proteins (typically Gαₒₗ𝒻). Despite its classification, the exact ligands and precise functional mechanisms of OR13C9 remain poorly characterized compared to well-studied ORs. Recent research has explored its potential ectopic expression in non-olfactory tissues, suggesting possible roles in cellular processes beyond smell perception, though conclusive evidence is lacking. Recombinant OR13C9 protein production, often achieved through heterologous expression in mammalian cell lines (e.g., HEK293) or cell-free systems, enables structural and functional studies to decipher its activation patterns and ligand specificity. Investigating OR13C9 contributes to understanding the combinatorial coding of odors and may have implications for designing biosensors or therapeutic targets for smell-related disorders.
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