关键信息
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基因名
IL-7RA
- 应用
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别名
CDw127
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种属
Human
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表达系统
E. coli
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标签
N- His & C- Myc
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纯度
Greater than 85% as determined by SDS-PAGE. as determined by SDS-PAGE.
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蛋白编号
P16871
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表达区间
21-239aa
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分子量
30.3 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
Interleukin-7 receptor alpha (IL-7RA) is a pivotal component of the immune system, playing a crucial role in lymphocyte development, differentiation, and homeostasis. It is primarily involved in the signaling pathways of cytokines, particularly in the proliferation and survival of T and B cells. Dysregulation or mutations in IL-7RA have been associated with various immunological disorders, including severe combined immunodeficiency (SCID) and autoimmune diseases. The therapeutic potential of recombinant IL-7RA proteins has garnered significant interest due to their ability to enhance immune responses, particularly in the context of cancer and viral infections. Research into the structure, function, and mechanisms of IL-7RA has led to advancements in understanding its role in immune regulation. Additionally, recombinant forms of IL-7RA are being explored for their potential in restoring immune function in immunocompromised patients and improving the effectiveness of immunotherapies. Investigating IL-7RA-based therapies could provide novel approaches to treat a wide range of diseases, highlighting its importance in both basic and translational immunology research.
