Cat: PA1000-5404

Recombinant Human REG1B Protein,His

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关键信息

  • 基因名

    REG1B

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    REG1B;PSPS2;REGL;Lithostathine-1-beta

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    P48304

  • 表达区间

    1-166aa

  • 氨基酸序列

    MAQTNSFFML ISSLMFLSLS QGQESQTELP NPRISCPEGT NAYRSYCYYF NEDPETWVDA DLYCQNMNSG NLVSVLTQAE GAFVASLIKE SSTDDSNVWI GLHDPKKNRR WHWSSGSLVS YKSWDTGSPS SANAGYCASL TSCSGFKKWK DESCEKKFSF VCKFKN

  • 分子量

    18 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

REG1B, a member of the regenerating gene family, has garnered significant attention due to its potential role in various biological processes and diseases. Initially identified in the context of pancreatic regeneration, REG1B is implicated in cellular responses to injury and inflammation. Research indicates that REG1B may play a part in cell proliferation, differentiation, and survival, suggesting its involvement in tumor biology and cancer progression. Elevated expression levels of REG1B have been observed in several types of cancer, including pancreatic, gastric, and colorectal cancers, leading to interest in its potential as a diagnostic or prognostic biomarker. Additionally, REG1B has been linked to the modulation of immune responses, indicating a possible role in autoimmune diseases and inflammatory disorders. The study of REG1B’s structure and function can provide insights into its mechanism of action and therapeutic potential, as targeting REG1B pathways may offer novel strategies for cancer treatment and regenerative medicine. Overall, the multifaceted roles of REG1B in health and disease underscore its importance as a subject of ongoing research in the fields of molecular biology and oncology.

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