Cat: PA2000-2280

Recombinant Human ZNF160 Protein,His

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关键信息

  • 基因名

    ZNF160

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    ZNF160;KIAA1611;Zinc finger Protein 160

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    His tag N-Terminus

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    Q9HCG1

  • 表达区间

    1-147aa

  • 氨基酸序列

    MALTQVRLTFRDVAIEFSQEEWKCLDPAQRILYRDVMLENYWNLVSLGLCHFDMNIISMLEEGKEPWTVKSCVKIARKPRTPECVKGVVTDLLRRWKHWLLLLGICCPKPHGRVSSRLRLSRSLGHFFHSAFATFMGVCDKRVGSIF

  • 分子量

    22.1 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

ZNF160, a member of the zinc finger protein family, has garnered significant attention in molecular biology and genetics due to its potential roles in transcriptional regulation, cellular differentiation, and development. Research has shown that zinc finger proteins are critical in mediating protein-DNA interactions, thereby influencing gene expression and cellular function. ZNF160 is particularly interesting because it contains multiple zinc finger motifs, suggesting a complex regulatory role in various biological processes. Recent studies have indicated its involvement in pathways related to cell growth and survival, as well as its potential implications in diseases such as cancer. The recombinant expression of ZNF160 allows for detailed functional analysis of this protein, enabling researchers to dissect its role in specific cellular contexts. By producing ZNF160 in heterologous systems, such as bacterial or yeast models, scientists can purify the protein and perform biochemical assays to determine its DNA-binding properties, interactome, and downstream effects. Understanding the mechanisms by which ZNF160 operates could provide insights into its potential applications in therapeutic strategies, particularly in targeting aberrant gene expression in diseases. Thus, the study of ZNF160 recombinant protein not only enhances our understanding of zinc finger proteins' biological functions but also opens avenues for developing novel diagnostic and therapeutic approaches in regenerative medicine and oncology.

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