关键信息
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基因名
C22orf18
- 应用
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别名
CENPM; C22orf18; ICEN39; PANE1Centromere Protein M; CENP-M; Interphase centromere complex Protein 39; Proliferation-associated nuclear element Protein 1
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9NSP4
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表达区间
1-180aa
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氨基酸序列
MSVLRPLDKLPGLNTATILLVGTEDALLQQLADSMLKEDCASELKVHLAKSLPLPSSVNRPRIDLIVFVVNLHSKYSLQNTEESLRHVDASFFLGKVCFLATGAGRESHCSIHRHTVVKLAHTYQSPLLYCDLEVEGFRATMAQRLVRVLQICAGHVPGVSALNLLSLLRSSEGPSLEDL
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分子量
45.54 KDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
C22orf18, also known as chromosome 22 open reading frame 18, has garnered attention in biochemical and genetic research due to its potential implications in various biological processes and diseases. Initially identified through genomic sequencing efforts, C22orf18 is hypothesized to play a significant role in cellular signaling and metabolic pathways, although its precise function remains largely unexplored. Recent studies have suggested that C22orf18 may be involved in cancer biology, particularly in the context of tumor growth and metastasis, making it a candidate for further investigation in cancer therapy. The generation of recombinant C22orf18 protein allows researchers to study its structure and function in detail. By expressing this protein in suitable expression systems, scientists can analyze its interactions with other cellular components and elucidate its role in downstream signaling pathways. Investigating the post-translational modifications and localization patterns of C22orf18 can provide insights into its functional mechanisms. Furthermore, understanding the implications of C22orf18 in disease pathology could reveal novel therapeutic targets, paving the way for innovative treatment strategies. Overall, the study of C22orf18 recombinant protein is a crucial step in unraveling the biological significance of this enigmatic protein and its potential impact on human health.
