关键信息
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基因名
SC4MOL
- 应用
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别名
Methylsterol monooxygenase 1. EC:1.14.18.9. C-4 methylsterol oxidase. Sterol-C4-methyl oxidase
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15800
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表达区间
1-293 aa
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氨基酸序列
MATNESVSIFSSASLAVEYVDSLLPENPLQEPFKNAWNYMLNNYTKFQIATWGSLIVHEALYFLFCLPGFLFQFIPYMKKYKIQKDKPETWENQWKCFKVLLFNHFCIQLPLICGTYYFTEYFNIPYDWERMPRWYFLLARCFGCAVIEDTWHYFLHRLLHHKRIYKYIHKVHHEFQAPFGMEAEYAHPLETLILGTGFFIGIVLLCDHVILLWAWVTIRLLETIDVHSGYDIPLNPLNLIPFYAGSRHHDFHHMNFIGNYASTFTWWDRIFGTDSQYNAYNEKRKKFEKKTE
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分子量
57.97 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
SC4MOL, or sterol carrier protein 4 (SCP4) with modulation of lipid metabolism, has garnered attention in recent years due to its pivotal role in cellular processes, particularly in cholesterol and sterol metabolism. As a member of the steroidogenic acute regulatory protein (StAR) family, SC4MOL facilitates the transport of various lipophilic molecules, which is crucial for maintaining cellular homeostasis and regulating membrane integrity. The disruption of SC4MOL function has been linked to various diseases, including metabolic disorders, cardiovascular diseases, and certain cancers, thereby highlighting its significance in health and disease. Research has focused on the structural characterization and functional analysis of SC4MOL to understand its mechanism of action better. Advances in recombinant protein technologies have enabled the production of SC4MOL in sufficient quantities for detailed studies, allowing scientists to investigate its interactions with other proteins, its role in lipid metabolism, and potential therapeutic targets. Understanding the intricate workings of SC4MOL is vital for developing innovative treatments for lipid-associated diseases and uncovering new aspects of metabolic regulation.
