关键信息
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基因名
DENND1A
- 应用
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别名
DENND1A；FAM31A；KIAA1608；DENN domain-containing Protein 1A
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8TEH3
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表达区间
1-559aa
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氨基酸序列
MGSRIKQNPETTFEVYVEVAYPRTGGTLSDPEVQRQFPEDYSDQEVLQTLTKFCFPFYVDSLTVSQVGQNFTFVLTDIDSKQRFGFCRLSSGAKSCFCILSYLPWFEVFYKLLNILADYTTKRQENQWNELLETLHKLPIPDPGVSVHLSVHSYFTVPDTRELPSIPENRNLTEYFVAVDVNNMLHLYASMLYERRILIICSKLSTLTACIHGSAAMLYPMYWQHVYIPVLPPHLLDYCCAPMPYLIGIHLSLMEKVRNMALDDVVILNVDTNTLETPFDDLQSLPNDVISSLKNRLKKVSTTTGDGVARAFLKAQAAFFGSYRNALKIEPEEPITFCEEAFVSHYRSGAMRQFLQNATQLQLFKQFIDGRLDLLNSGEGFSDVFEEEINMGEYAGSDKLYHQWLSTVRKGSGAILNTVKTKANPAMKTVYKFAKDHAKMGIKEVKNRLKQKDIAENGCAPTPEEQLPKTAPSPLVEAKDPKLREDRRPITVHFGQVRPPRPHVVKRPKSNIAVEGRRTSVPSPEQNTIATPATLHILQKSITHFAAKFPTRGWTSSSH
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分子量
79.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
DENND1A (Differentially Expressed in Normal and Neoplastic Development 1A) is a protein known for its role in intracellular trafficking and signaling pathways, particularly in the context of cancer biology and reproductive health. Its involvement in various cellular processes has drawn attention, as alterations in its expression or function may contribute to the progression of various diseases, including cancer and infertility. Research has highlighted DENND1A's potential as a biomarker for certain tumors, making it a subject of interest for therapeutic strategies. The study of DENND1A recombinant protein aims to elucidate its structure-function relationship and interactions with other molecular partners. Utilizing techniques such as recombinant DNA technology and protein expression systems, researchers can produce DENND1A in sufficient quantities for functional assays and structural studies. Understanding the molecular mechanisms influenced by DENND1A could reveal new insights into tumorigenesis and provide avenues for the development of novel therapeutic interventions. Furthermore, as DENND1A is implicated in reproductive processes, research into its recombinant form also holds promise for advancing fertility treatments. Overall, the study of DENND1A recombinant protein is a vital step toward unraveling its biological significance and potential clinical applications.
