关键信息
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基因名
SSR3
- 应用
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别名
SSR3; TRAPG; Translocon-associated Protein subunit gamma; TRAP-gamma; Signal sequence receptor subunit gamma; SSR-gamma
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9UNL2
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表达区间
1-185 aa
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氨基酸序列
MAPKGSSKQQSEEDLLLQDFSRNLSAKSSALFFGNAFIVSAIPIWLYRRIWHMDLIQSAVLYSVMTLVSTYLVAFAYKNVKFVLKHKVAQKREDAVSKEVTRKLSEADNRKMSRKEKDERILWKKNEVADYEATTFSIFYNNTLFLVVVIVASFFILKNFNPTVNYILSISASSGLIALLSTGSK
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分子量
46.09 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
SSR3, or Signal Sequence Repeats 3, is a protein that has garnered attention within the field of molecular biology due to its potential role in various cellular processes and its involvement in diseases. Initially identified as part of the signal recognition particle (SRP) pathway, SSR3 is known to facilitate the co-translational translocation of proteins into the endoplasmic reticulum (ER). Research into SSR3 has revealed its significance in maintaining protein homeostasis, as well as its involvement in the stress response mechanisms within the ER. Dysfunctions in SSR3 expression or function have been linked to several pathological conditions, including cancers and neurodegenerative diseases, making it a target of interest for therapeutic interventions. Recent studies have focused on characterizing the structure and function of SSR3 using recombinant protein techniques to elucidate its mechanisms of action, interactions with other cellular components, and potential as a biomarker for disease. Understanding the role of SSR3 in the cellular context is crucial for developing novel strategies aimed at modulating its expression or activity to combat diseases associated with ER stress and protein misfolding. Overall, research on SSR3 and its recombinant forms has the potential to pave the way for advancements in targeted therapies and enhance our understanding of cellular stress responses.
