Cat: PAX2000-11686

Recombinant Human ST18 Protein,GST

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关键信息

  • 基因名

    ST18

  • 应用

    SPRMSTBLIITCELISA细胞实验药物筛选

  • 别名

    Zinc finger Protein 387

  • 种属

    Human

  • 表达系统

    E. coli

  • 标签

    GST-tag at N-terminal

  • 纯度

    Greater than 90% as determined by SDS-PAGE.

  • 蛋白编号

    O60284

  • 表达区间

    120-260 aa

  • 氨基酸序列

    SCYQELMVKSLMHLGKFEKNVSVQTVSENLNDSGIQSLKAESDEADECFLIHSDDGRDKIDDSQPPFCSSDDNESNSESAENGWDSGSNFSEETKPPRVPKYVLTDHKKDLLEVPEIKTEGDKFIPCENRCDSETERKDPQ

  • 分子量

    23.4 kDa

  • 内毒素

    < 1.0 EU per μg protein as determined by the LAL method.

  • 性状

    Freeze-dried powder

  • 缓冲液

    PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.

  • 复溶方法

    Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.

  • 个性化定制

    点位突变 标签定制 buffer定制 全长蛋白定制

  • 稳定性测试

    The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.

  • 保存条件 & 期限

    Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

  • 运输条件

    In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.

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背景信息

ST18 is a gene that encodes a protein with potential roles in cellular stress response, apoptosis, and tumor progression, making it a subject of interest in cancer research. Recent studies have suggested that ST18 may act as a tumor suppressor in various malignancies by regulating pathways associated with cell survival and proliferation. Its expression levels have been linked to specific cancer types, indicating that ST18 might influence tumor characteristics and patient prognosis. Given the increase in cancer incidence globally, understanding the functional mechanisms of ST18 and the implications of its protein product could provide valuable insights into novel therapeutic strategies. Researchers are focusing on characterizing the ST18 recombinant protein to elucidate its functional properties, interactions with other cellular proteins, and regulatory mechanisms. These studies aim to establish a comprehensive understanding of ST18’s role in cellular pathways, which could ultimately contribute to the development of targeted therapies that leverage the protein's function in combating cancer. The characterization of ST18 and its associated pathways may also promote the discovery of biomarkers for early detection and treatment response, thereby enhancing clinical outcomes for cancer patients.

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