关键信息
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基因名
IL17D
- 应用
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别名
IL17D；Interleukin-17D
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q8TAD2
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表达区间
18-202aa
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氨基酸序列
APRAGRRPAR PRGCADRPEE LLEQLYGRLA AGVLSAFHHT LQLGPREQAR NASCPAGGRP ADRRFRPPTN LRSVSPWAYR ISYDPARYPR YLPEAYCLCR GCLTGLFGEE DVRFRSAPVY MPTVVLRRTP ACAGGRSVYT EAYVTIPVGC TCVPEPEKDA DSINSSIDKQ GAKLLLGPND APAGP
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分子量
41 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
Interleukin 17D (IL-17D) is a member of the IL-17 family of cytokines, which play a significant role in immune responses and inflammation. Its discovery in recent years has sparked interest due to its potential implications in various diseases, particularly autoimmune disorders, cancers, and infectious diseases. Research has shown that IL-17D is involved in promoting tissue inflammation and influencing the activation of immune cells. Unlike other IL-17 family members, the exact biological function of IL-17D remains less understood, necessitating further investigation. Studies have indicated that IL-17D may enhance the proliferation and activation of T cells, linking it to both adaptive and innate immune responses. Additionally, its expression has been associated with certain pathological conditions, raising the question of whether IL-17D could serve as a therapeutic target or biomarker for disease progression. The generation of recombinant IL-17D proteins is therefore essential for elucidating its biological role and therapeutic potential. This recombinant protein can be utilized to study the signaling pathways it activates, its interactions with immune cells, and its effects in vivo. Understanding IL-17D's mechanisms could pave the way for developing novel strategies to manage diseases where this cytokine plays a critical role, highlighting the importance of ongoing research in this area.
