关键信息
-
基因名
WDR13
- 应用
-
别名
DKFZp779C2057; FLJ20563; located at OATL1; MG21; WD repeat domain 13; WD repeat-containing Protein 13; WDR13; WDR13_HUMAN
-
种属
Human
-
表达系统
E. coli
-
标签
His tag N-Terminus
-
纯度
Greater than 90% as determined by SDS-PAGE.
-
蛋白编号
Q9H1Z4
-
表达区间
1-485 aa
-
氨基酸序列
MAAVWQQVLA VDARYNAYRT PTFPQFRTQY IRRRSQLLRE NAKAGHPPAL RRQYLRLRGQ LLGQRYGPLS EPGSARAYSN SIVRSSRTTL DRMEDFEDDP RALGARGHRR SVSRGSYQLQ AQMNRAVYED RPPGSVVPTS AAEASRAMAG DTSLSENYAF AGMYHVFDQH VDEAVPRVRF ANDDRHRLAC CSLDGSISLC QLVPAPPTVL RVLRGHTRGV SDFAWSLSND ILVSTSLDAT MRIWASEDGR CIREIPDPDS AELLCCTFQP VNNNLTVVGN AKHNVHVMNI STGKKVKGGS SKLTGRVLAL SFDAPGRLLW AGDDHGSVFS FLFDMATGKL TKAKRLVVHE GSPVTSISAR SWVSREARDP SLLINACLNK LLLYRVVDNE GTLQLKRSFP IEQSSHPVRS IFCPLMSFRQ GACVVTGSED MCVHFFDVER AAKAAVNKLQ GHSAPVLDVS FNCDESLLAS SDASGMVIVW RREQK
-
分子量
53.7 kDa
-
内毒素
< 1.0 EU per μg protein as determined by the LAL method.
-
性状
Freeze-dried powder
-
缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
-
复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
-
稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
-
保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
-
运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
WDR13, or WD repeat domain 13, is a protein implicated in various cellular processes, including protein-protein interactions, cell signaling, and cytoskeletal organization, mainly due to its multiple WD40 repeats. Research into WDR13 has gained traction as its dysregulation has been linked to several diseases, particularly metabolic disorders and cancer. The necessity of understanding WDR13's functional mechanisms arises from its potential role in the pathogenesis of these conditions, making it a candidate for therapeutic targets. Constructing recombinant WDR13 proteins enables scientists to study their structure-function relationships and interactions with other cellular components in vitro. This understanding can shed light on the molecular pathways in which WDR13 is involved and may reveal novel insights into how alterations in its function contribute to disease progression. Moreover, recombinant WDR13 can facilitate the development of specific inhibitors or modulators, opening avenues for new treatments. As the field of protein research expands, the production and characterization of WDR13 in a recombinant form stand as a crucial step toward elucidating its role in health and disease.
