关键信息
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基因名
SDC3
- 应用
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别名
SDC3；KIAA0468；Syndecan-3
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75056
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表达区间
1-442aa
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氨基酸序列
MKPGPPHRAGAAHGAGAGAGAAAGPGARGLLLPPLLLLLLAGRAAGAQRWRSENFERPVDLEGSGDDDSFPDDELDDLYSGSGSGYFEQESGIETAMRFSPDVALAVSTTPAVLPTTNIQPVGTPFEELPSERPTLEPATSPLVVTEVPEEPSQRATTVSTTMATTAATSTGDPTVATVPATVATATPSTPAAPPFTATTAVIRTTGVRRLLPLPLTTVATARATTPEAPSPPTTAAVLDTEAPTPRLVSTATSRPRALPRPATTQEPDIPERSTLPLGTTAPGPTEVAQTPTPETFLTTIRDEPEVPVSGGPSGDFELPEEETTQPDTANEVVAVGGAAAKASSPPGTLPKGARPGPGLLDNAIDSGSSAAQLPQKSILERKEVLVAVIVGGVVGALFAAFLVTLLIYRMKKKDEGSYTLEEPKQASVTYQKPDKQEEFYA
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分子量
45.4 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
SDC3, or syndecan-3, is a member of the syndecan family of transmembrane heparan sulfate proteoglycans, which play critical roles in cell signaling, adhesion, and the extracellular matrix structure. It is particularly expressed in neural tissues and has been implicated in various physiological processes, including neural development and repair. Recent studies have highlighted its potential involvement in neuronal differentiation and synaptic formation, suggesting that SDC3 may influence neuroplasticity and regeneration following injury. Given its specific expression in the central nervous system and its interaction with growth factors and extracellular matrix components, researchers are increasingly focused on understanding the molecular mechanisms through which SDC3 mediates its effects. Moreover, the recombinant production of SDC3 protein provides a valuable tool for investigating its functional properties in vitro and in vivo, facilitating the exploration of its potential therapeutic applications in neurodegenerative diseases and spinal cord injuries. Understanding the structural and functional characteristics of SDC3 can aid in developing novel strategies for neural regeneration and highlight its significance in maintaining nervous system homeostasis. As research progresses, SDC3 is emerging as a key player in the intricate networks of cellular communication and signaling in the brain, underscoring the importance of proteoglycans in neurobiology.
