关键信息
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基因名
CABIN1
- 应用
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别名
CABIN1；KIAA0330；Calcineurin-binding Protein cabin-1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q9Y6J0
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表达区间
全长
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氨基酸序列
full
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CABIN1 (Calmodulin-Binding Protein 1) is a multifunctional protein that plays a crucial role in various cellular processes, including immune responses and transcription regulation. Emerging research has highlighted its importance in T cell signaling and differentiation, as CABIN1 interacts with key signaling molecules such as calmodulin and nuclear receptor co-repressors. Its involvement in immune modulation makes it a significant factor in autoimmune diseases and cancer, where dysregulation of immune responses is often observed. Recent studies have focused on the structural and functional characterization of CABIN1 to better understand its mechanisms of action. These investigations aim to explore how CABIN1 regulates gene expression and its potential as a therapeutic target. Furthermore, by elucidating the pathways through which CABIN1 operates, researchers hope to uncover novel approaches for enhancing immune responses or mitigating autoimmunity. The growing body of literature suggests that CABIN1 may also serve as a biomarker for certain diseases, mediated by its expression levels in immune cells. Thus, the study of CABIN1 is not only pivotal in understanding basic immunological principles but also holds promise for developing innovative treatments for immune-related disorders. Overall, CABIN1 stands out as a protein of significant interest in both basic and translational research, with potential implications for improving human health through targeted therapies.
