关键信息
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基因名
BMP8A
- 应用
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别名
BMP8A；Bone morphogenetic Protein 8A
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q7Z5Y6
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表达区间
264-402aa
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氨基酸序列
AVRPLRR RQPKKSNELP QANRLPGIFD DVRGSHGRQV CRRHELYVSF QDLGWLDWVI APQGYSAYYC EGECSFPLDS CMNATNHAIL QSLVHLMKPN AVPKACCAPT KLSATSVLYY DSSNNVILRK HRNMVVKACG CH
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
BMP8A, or Bone Morphogenetic Protein 8A, is a member of the transforming growth factor-beta (TGF-β) superfamily, which plays a crucial role in various physiological processes such as bone development, regulation of cell growth, and differentiation. Initially identified for its significant role in osteogenesis, BMP8A has garnered attention for its involvement in metabolic pathways, particularly in energy homeostasis and adipogenesis. Research has demonstrated that BMP8A can influence metabolic functions in brown adipose tissue, potentially affecting thermogenesis and energy expenditure. Furthermore, its role in the regulation of insulin sensitivity and its implications in metabolic disorders, such as obesity and diabetes, have led to increased interest in BMP8A as a therapeutic target. The recombinant production of BMP8A protein has become essential for studying its biological functions and mechanisms, enabling researchers to explore its potential applications in regenerative medicine and metabolic disease management. Understanding the structural and functional properties of BMP8A through recombinant technology could provide insights into novel therapeutic strategies, contributing to advances in both tissue engineering and metabolic health. Consequently, BMP8A is not only a key player in developmental biology but also presents opportunities for innovative treatments in metabolic-related diseases.
