关键信息
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基因名
ZSWIM7
- 应用
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别名
Zinc finger SWIM domain-containing protein 7. SWIM domain-containing and Srs2-interacting protein 1 homolog. SWIM-type zinc finger domain-containing protein 7
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q19AV6
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表达区间
1-140 aa
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氨基酸序列
MAVVLPAVVEELLSEMAAAVQESARIPDEYLLSLKFLFGSSATQALDLVDRQSITLISSPSGRRVYQVLGSSSKTYTCLASCHYCSCPAFAFSVLRKSDSILCKHLLAVYLSQVMRTCQQLSVSDKQLTDILLMEKKQEA
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分子量
41.8 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
ZSWIM7, a member of the ZSWIM family of proteins, has emerged as a significant focus of research due to its potential roles in cellular processes and disease mechanisms. This protein contains a unique combination of zinc finger motifs, which are critical for DNA binding and protein-protein interactions, suggesting its involvement in regulating gene expression and chromatin remodeling. Initial studies have linked ZSWIM7 to various biological functions, including cell proliferation, apoptosis, and differentiation, indicating its importance in developmental biology and disease states. Aberrant expression or mutations in ZSWIM7 have been associated with several cancers, highlighting its potential as a biomarker and therapeutic target. Research efforts have increasingly aimed at elucidating the molecular pathways influenced by ZSWIM7, as well as its interactions with other key proteins in the cellular environment. Understanding the precise mechanisms by which ZSWIM7 operates could pave the way for novel interventions in cancer treatment and regenerative medicine, making it an intriguing subject for ongoing investigations in molecular biology and clinical research.
