关键信息
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基因名
ADIPOR1
- 应用
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别名
ADIPOR1；PAQR1；TESBP1A；Adiponectin receptor Protein 1
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q96A54
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表达区间
89-375aa
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氨基酸序列
EGRWRVIPYD VLPDWLKDND YLLHGHRPPM PSFRACFKSI FRIHTETGNI WTHLLGFVLF LFLGILTMLR PNMYFMAPLQ EKVVFGMFFL GAVLCLSFSW LFHTVYCHSE KVSRTFSKLD YSGIALLIMG SFVPWLYYSF YCSPQPRLIY LSIVCVLGIS AIIVAQWDRF ATPKHRQTRA GVFLGLGLSG VVPTMHFTIA EGFVKATTVG QMGWFFLMAV MYITGAGLYA ARIPERFFPG KFDIWFQSHQ IFHVLVVAAA FVHFYGVSNL QEFRYGLEGG CTDDTLL
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分子量
35 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
ADIPOR1 (adiponectin receptor 1) is a critical receptor involved in the metabolic pathways influenced by adiponectin, a hormone secreted by adipose tissue that plays a significant role in regulating glucose levels and fatty acid breakdown. Research has highlighted ADIPOR1's potential implications in various metabolic disorders, including obesity, insulin resistance, and type 2 diabetes. The receptor is known to mediate the beneficial metabolic effects of adiponectin, which include enhancing insulin sensitivity and promoting lipid metabolism. Understanding the structure and function of ADIPOR1 is essential for developing therapeutic strategies targeting these metabolic diseases. Recombinant ADIPOR1 protein has been extensively studied to elucidate its signaling mechanisms and biological functions. By producing this receptor in a controlled laboratory environment, scientists can analyze its interaction with adiponectin and other signaling molecules, paving the way for novel interventions. Furthermore, the study of ADIPOR1 can aid in understanding the receptor's role in the pathophysiology of metabolic syndrome, as well as its potential as a biomarker for disease progression. Overall, the investigation of ADIPOR1 not only furthers our comprehension of metabolic regulation but also holds promise for innovative treatment options for metabolic disorders by targeting the adiponectin signaling pathway.
