关键信息
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基因名
FOXD4L6
- 应用
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别名
FOXD4L6Forkhead box protein D4-like 6; FOXD4-like 6
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种属
Human
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表达系统
E. coli
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标签
GST-tag at N-terminal
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q3SYB3
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表达区间
1-417aa
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氨基酸序列
MNLPRAERLR STPQRSLRDS DGEDGKIDVL GEEEDEDEVE DEEEAASQQF LEQSLQPGLQ VARWGGVALP REHIEGGGGP SDPSEFGTKF RAPPRSAAAS EDARQPAKPP YSYIALITMA ILQNPHKRLT LSGICAFISG RFPYYRRKFP AWQNSIRHNL SLNDCFVKIP REPGHPGKGN YWSLDPASQD MFDNGSFLRR RKRFKRHQLT PGAHLPHPFP LPAAHAALHN PHPGPLLGAP APPQPVPGAY PNTAPGRRPY ALLHPHPLRY LLLSAPVYAG APKKAEGAAL ATPAPFPCCS PHLVLSLGRR ARVWRRHREA DASLSALRVL CKGSGERVQG LRRVCPRPRG ATATCSSDHQ ACCIPRPLPL CCKCPPPPLL GQFCSNSSSI RRRTAPTAAL PPRARCWAGT CRPRRPC
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分子量
45.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
FOXD4L6, a member of the forkhead box (FOX) family of transcription factors, has garnered interest in recent years due to its potential roles in developmental biology and disease processes. It is primarily expressed during embryogenesis and is implicated in various regulatory pathways that influence organogenesis and cellular differentiation. Studies have shown that FOXD4L6 is involved in the regulation of genes related to neuronal development and may play a crucial role in maintaining stem cell pluripotency. Furthermore, alterations in the expression of FOXD4L6 have been linked to several pathologies, including cancers, where it may contribute to tumorigenesis through the modulation of proliferation and apoptosis. As a result, the research focus has shifted towards the characterization and functional analysis of FOXD4L6 recombinant proteins to better understand its mechanisms of action. Recombinant expression systems allow for the production of FOXD4L6 in sufficient quantities, facilitating structural studies and functional assays. These investigations aim to elucidate the molecular pathways regulated by FOXD4L6, providing insights into its biological significance and evaluating its potential as a therapeutic target in diseases associated with dysregulated FOXD4L6 activity.
