关键信息
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基因名
PDGFRL
- 应用
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别名
PDGFRL；ASH；Growth factor receptor-bound Protein 2
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种属
Human
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表达系统
E. coli
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标签
His tag N-Terminus
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
Q15198
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表达区间
22-375aa
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氨基酸序列
QHLPKNKRP KEPGENRIKP TNKKVKPKIP KMKDRDSANS APKTQSIMMQ VLDKGRFQKP AATLSLLAGQ TVELRCKGSR IGWSYPAYLD TFKDSRLSVK QNERYGQLTL VNSTSADTGE FSCWVQLCSG YICRKDEAKT GSTYIFFTEK GELFVPSPSY FDVVYLNPDR QAVVPCRVTV LSAKVTLHRE FPAKEIPANG TDIVYDMKRG FVYLQPHSEH QGVVYCRAEA GGRSQISVKY QLLYVAVPSG PPSTTILASS NKVKSGDDIS VLCTVLGEPD VEVEFTWIFP GQKDERPVTI QDTWRLIHRG LGHTTRISQS VITVEDFETI DAGYYICTAQ NLQGQTTVAT TVEFS
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
PDGFRL (Platelet-Derived Growth Factor Receptor-Like) is a member of the PDGF receptor family, which is involved in various cellular processes, including proliferation, differentiation, and migration. It is known to play a crucial role in the development of multiple tissues and may have implications in pathological conditions such as cancer and fibrosis. Research into PDGFRL is particularly significant due to its potential as a therapeutic target; however, its function and underlying mechanisms remain poorly understood compared to other PDGF receptors. Recent studies have indicated that PDGFRL could be involved in modulating signaling pathways that regulate cell survival and immune responses. The expression of PDGFRL in different cell types and its interaction with other ligands and receptors highlight its complexity and importance in cellular communication. Recombinant PDGFRL proteins have become essential tools for investigating its biological functions and interactions in vitro and in vivo, thereby paving the way for potential clinical applications. Understanding the mechanisms by which PDGFRL operates could provide insights into new therapeutic strategies for diseases where PDGFRL is implicated, making it a target of interest in both basic and translational research.
