| WB | 咨询技术 | Human, Monkey |
| IF | 咨询技术 | Human, Monkey |
| IHC | 1/200-1/1000 | Human, Monkey |
| ICC | 1/200 - 1/1000 | Human, Monkey |
| FCM | 1/200-1/400 | Human, Monkey |
| Elisa | 1/10000 | Human, Monkey |
| Aliases | HSA; PRO0883; PRO0903; PRO1341 |
| Entrez GeneID | 213 |
| clone | 1F5H7 |
| WB Predicted band size | 69.4kDa |
| Host/Isotype | Mouse IgG2b |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Monkey |
| Immunogen | Purified recombinant fragment of human ALB (AA: 410-609) expressed in E. Coli. |
| Formulation | Purified antibody in PBS with 0.05% sodium azide |
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以下是3-4条关于ALB(白蛋白)抗体的参考文献示例(内容为模拟概括，非真实文献)：
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1. **文献名称**：*"Development of a High-Specificity Anti-Human Albumin Monoclonal Antibody for Diagnostic Applications"*
**作者**：Smith J, et al.
**摘要**：研究报道了一种新型抗人白蛋白单克隆抗体的开发，通过杂交瘤技术筛选出高特异性的抗体，适用于ELISA和免疫组化检测，验证其在临床样本中对白蛋白的灵敏度和准确性。
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2. **文献名称**：*"Albumin Autoantibodies in Autoimmune Diseases: Clinical Significance and Detection Methods"*
**作者**：Li Y, et al.
**摘要**：探讨了自身免疫性疾病患者血清中抗白蛋白自身抗体的存在及其与疾病活动性的关联，比较了免疫印迹法和化学发光法在检测中的性能差异。
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3. **文献名称**：*"Cross-Reactivity of Anti-Albumin Antibodies with Animal Albumins in Biomedical Research"*
**作者**：Garcia R, et al.
**摘要**：分析了不同物种(小鼠、大鼠、牛)白蛋白与抗人白蛋白抗体的交叉反应性，为实验设计中抗体选择提供参考，减少非特异性结合的干扰。
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4. **文献名称**：*"Albumin-Binding Antibodies as Drug Carriers: A Novel Therapeutic Strategy"*
**作者**：Wang H, et al.
**摘要**：提出利用抗白蛋白抗体与白蛋白的高亲和力特性，设计靶向药物递送系统，通过动物模型验证其在肿瘤治疗中的增效作用。
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如需真实文献，建议通过PubMed或Google Scholar检索关键词“albumin antibody”或“anti-albumin antibodies”，并筛选近年高被引研究。
Albumin (ALB) antibodies are immunological tools targeting albumin, a highly abundant plasma protein synthesized primarily in the liver. As the most prevalent protein in human blood (35–50 g/L), albumin plays critical roles in maintaining osmotic pressure, transporting hormones/fatty acids, and regulating pH. ALB antibodies are widely utilized in research, diagnostics, and therapeutic development due to albumin's physiological and pathological significance.
In research, ALB antibodies enable quantitative detection (ELISA, Western blot) and tissue localization (immunohistochemistry) of albumin, aiding studies on liver function, vascular permeability, and metabolic disorders. Commercially available ALB antibodies are typically raised in rabbits, mice, or goats, with both monoclonal (high specificity) and polyclonal (broad epitope recognition) variants. Cross-reactivity across species (e.g., human, mouse, rat) is common due to albumin's structural conservation.
Clinically, ALB antibodies support diagnostic assays for hypoalbuminemia (liver/kidney diseases) and monitor conditions like nephrotic syndrome. Emerging therapeutic applications include antibody-drug conjugates targeting albumin-bound molecules and neutralizing antibodies for rare albumin-related autoimmune conditions. Recent advances in recombinant antibody technology have improved batch consistency and reduced non-specific binding, enhancing their utility in precision medicine. Validation remains crucial, as endogenous albumin abundance can interfere with assay sensitivity in biological samples.
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