| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
| Aliases | CT73; svph1 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Synthetic peptide of human ADAM29 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是3篇关于ADAM29抗体的参考文献示例(文献信息为模拟虚构，仅供格式参考)：
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1. **文献名称**: "ADAM29 Expression in Acute Myeloid Leukemia: A Potential Biomarker for Disease Progression"
**作者**: Smith J, et al.
**摘要**: 该研究利用ADAM29特异性抗体，通过免疫组化检测AML患者骨髓样本中ADAM29的蛋白表达，发现其高表达与患者预后不良显著相关，提示ADAM29可能作为白血病治疗的潜在靶点。
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2. **文献名称**: "Functional Characterization of ADAM29 in Prostate Cancer Cell Invasion"
**作者**: Lee H, et al.
**摘要**: 通过Western blot和流式细胞术验证ADAM29抗体特异性，发现ADAM29在前列腺癌细胞中高表达，并促进肿瘤细胞迁移和侵袭。抗体阻断实验表明ADAM29可能通过调节EGFR信号通路发挥作用。
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3. **文献名称**: "ADAM29 Antibody Development and Validation for Immunohistochemical Staining"
**作者**: Garcia R, et al.
**摘要**: 本研究开发了一种高灵敏度的兔源ADAM29多克隆抗体，通过质谱和敲除细胞系验证其特异性。该抗体成功应用于结肠癌组织切片，显示ADAM29在肿瘤间质中的表达与转移风险相关。
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**提示**：以上文献为示例，真实文献需通过PubMed或Google Scholar搜索关键词“ADAM29 antibody”、“ADAM29 cancer”等获取。建议优先选择近5年发表的论文以确保研究前沿性。
ADAM29 (A Disintegrin And Metalloprotease domain 29) is a member of the ADAM family of transmembrane proteins, which are characterized by their dual roles in cell adhesion and proteolytic processing. These proteins typically consist of a prodomain, metalloprotease domain, disintegrin domain, cysteine-rich region, and a transmembrane segment. ADAM29 is primarily expressed in immune cells, such as lymphocytes, and has been implicated in regulating cell-cell interactions, signaling pathways, and extracellular matrix remodeling. While its exact physiological functions remain under investigation, studies suggest its involvement in immune responses and pathological conditions, including cancer.
ADAM29 antibodies are tools used to detect and study the protein's expression, localization, and function in biological samples. Research has linked ADAM29 to cancer progression, particularly in hematological malignancies and solid tumors, where its dysregulated expression may influence tumor cell migration, invasion, or immune evasion. Antibodies targeting ADAM29 enable investigations into its role in these processes via techniques like Western blotting, immunohistochemistry, and flow cytometry. Additionally, ADAM29 antibodies hold potential for diagnostic or therapeutic applications, as abnormal ADAM29 levels could serve as biomarkers or targets in certain cancers. However, further studies are needed to fully elucidate its mechanisms and clinical relevance.
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