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Rabbit Polyclonal DIPK2B Antibody

  • 中文名: DIPK2B抗体
  • 别    名: DIA1R; CXorf36; PRO3743; EPQL1862; bA435K1.1; 4930578C19Rik
货号: IPDX04806
Price: ¥1180
数量:
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验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/25-1/100 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 1/5000-1/10000 Human,Mouse,Rat

产品详情

AliasesDIA1R; CXorf36; PRO3743; EPQL1862; bA435K1.1; 4930578C19Rik
WB Predicted band size49 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human DIPK2B
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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参考文献

以下是基于假设的示例性参考文献,用于演示格式。请注意,这些文献为虚构创作,实际研究中可能不存在:

1. **文献名称**: "Development and Validation of a DIPK2B-Specific Monoclonal Antibody for Functional Studies"

**作者**: Chen, L., et al.

**摘要**: 本研究开发并验证了一种新型小鼠单克隆抗体,用于检测人类DIPK2B蛋白。通过免疫印迹和免疫荧光证实其特异性,应用于探究DIPK2B在肝癌细胞迁移中的作用。

2. **文献名称**: "DIPK2B Antibody Reveals Its Role in Neuronal Axon Guidance via BMP Signaling"

**作者**: Kim, S., & Park, H.

**摘要**: 利用兔多克隆抗体研究DIPK2B在斑马鱼神经元发育中的功能,发现其通过调控BMP信号通路参与轴突导向,抗体特异性通过基因敲除实验验证。

3. **文献名称**: "A High-Affinity DIPK2B Antibody Identifies Its Epigenetic Regulatory Role in Colon Cancer"

**作者**: Gonzalez, R., et al.

**摘要**: 通过制备高亲和力抗体,结合ChIP-seq技术揭示DIPK2B与组蛋白修饰酶相互作用,在结肠癌中调控基因沉默的机制。

**注意**:DIPK2B相关研究较少,上述内容为示例。建议用户:

1. 确认术语准确性(如是否应为DIP2B或其他变体);

2. 在PubMed或Google Scholar中以“DIPK2B antibody”或“DIPK2B function”为关键词检索真实文献;

3. 查阅相关领域综述获取线索。

背景信息

The DIPK2B antibody is designed to target the Disco-interacting protein 2B (DIPK2B), a less-characterized protein implicated in cellular signaling and structural regulation. DIPK2B belongs to a conserved protein family with potential roles in cell adhesion, cytoskeletal organization, and intracellular trafficking, though its precise molecular functions remain under investigation. Studies suggest associations with neurological processes and developmental pathways, possibly interacting with DISC1 (Disrupted in Schizophrenia 1), a protein linked to neuropsychiatric disorders. The antibody, typically produced in hosts like rabbits or mice using immunogenic peptide fragments, enables detection of DIPK2B expression in various experimental models via techniques like Western blotting, immunohistochemistry, or immunofluorescence. Its development supports ongoing research into DIPK2B's involvement in diseases such as cancer, neurodegenerative conditions, or psychiatric disorders, where aberrant expression or mutations may contribute to pathogenesis. Validated for specificity and sensitivity, this tool aids in elucidating DIPKK2B's subcellular localization, interaction networks, and regulatory mechanisms, offering insights into its biological and clinical relevance.

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