| WB | 1/200-1/1000 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/1000-1/2000 | Human,Mouse,Rat |
| Aliases | LC17; ESMLC; LC17A; LC17B; MLC-3; MLC1SM; MLC3NM; MLC3SM; LC17-GI; LC17-NM |
| WB Predicted band size | 17 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Fusion protein of human MYL6 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
+ +
以下是关于MYL6抗体的虚构示例参考文献(仅供示例参考，实际文献请通过学术数据库查询)：
1. **文献名称**: "MYL6 as a novel biomarker in colorectal cancer: Validation by immunohistochemistry"
**作者**: Chen L, et al.
**摘要**: 本研究通过免疫组化技术验证了MYL6抗体在结直肠癌组织中的特异性表达，发现MYL6高表达与患者预后不良相关，提示其可能作为潜在的肿瘤标志物。
2. **文献名称**: "Characterization of MYL6 antibody for detecting myosin light chain isoforms in cardiomyocytes"
**作者**: Tanaka S, et al.
**摘要**: 该文献报道了一种高特异性MYL6抗体的开发，用于区分心肌细胞中不同的肌球蛋白轻链亚型，并证实其在心脏疾病模型中的功能研究价值。
3. **文献名称**: "MYL6 regulates intracellular vesicle trafficking via interaction with motor proteins"
**作者**: Gupta R, et al.
**摘要**: 研究利用MYL6抗体进行免疫共沉淀实验，揭示了MYL6通过调控马达蛋白相互作用参与细胞内囊泡运输的分子机制。
---
**注意**：以上文献为模拟内容，实际文献需通过**PubMed**、**Web of Science**或**Google Scholar**等平台检索。建议使用关键词“MYL6 antibody”、“MYL6 function”或结合具体研究领域(如癌症、细胞生物学)进行筛选。
**Background of MYL6 Antibody**
MYL6 (Myosin Light Chain 6) is a protein encoded by the *MYL6* gene and belongs to the myosin light chain family, which regulates the function of myosin—a motor protein critical for muscle contraction, cell motility, and intracellular transport. MYL6 specifically associates with myosin heavy chains in non-muscle cells and smooth muscle tissues, forming part of the myosin II complex. This complex plays a role in cytoskeletal organization, cytokinesis, and maintaining cell shape.
The MYL6 antibody is a laboratory tool designed to detect and quantify MYL6 protein expression in biological samples. It is commonly used in techniques such as Western blotting, immunofluorescence, and immunohistochemistry to study MYL6’s localization, expression levels, and interactions in various cellular contexts. Research involving MYL6 antibodies has shed light on its involvement in cellular processes like vesicle trafficking, cell adhesion, and mechanotransduction.
Dysregulation of MYL6 has been implicated in pathological conditions, including cardiovascular diseases and cancer metastasis, where altered cytoskeletal dynamics contribute to disease progression. MYL6 antibodies thus serve as valuable reagents for both basic research and clinical investigations, aiding in the understanding of myosin-mediated mechanisms and their therapeutic targeting. Commercial MYL6 antibodies are typically validated for specificity and sensitivity, often targeting conserved epitopes across species to support cross-disciplinary studies.
×
