首页 / 产品 / 抗体 / 一抗

Rabbit Polyclonal C1QTNF6 Antibody

  • 中文名: C1QTNF6抗体
  • 别    名: CTFP6; CTRP6; ZACRP6
货号: IPDX07690
Price: ¥1180
数量:
大包装询价

验证与应用

应用及物种
WB 咨询技术 Human,Mouse,Rat
IF 咨询技术 Human,Mouse,Rat
IHC 1/25-1/100 Human,Mouse,Rat
ICC 技术咨询 Human,Mouse,Rat
FCM 咨询技术 Human,Mouse,Rat
Elisa 1/2000-1/5000 Human,Mouse,Rat

产品详情

AliasesCTFP6; CTRP6; ZACRP6
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human C1QTNF6
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

参考文献

以下是3篇与C1QTNF6抗体相关的模拟参考文献(内容为示例,非真实文献):

1. **"C1QTNF6 promotes tumor angiogenesis through VEGF signaling in colorectal cancer"**

*作者:Zhang Y, et al. (2022)*

*摘要*:研究揭示了C1QTNF6在结直肠癌中通过激活VEGF通路促进肿瘤血管生成的作用,并开发了特异性单克隆抗体用于阻断其功能,抑制小鼠模型中肿瘤生长。

2. **"Anti-C1QTNF6 antibody ameliorates adipose tissue inflammation in obesity"**

*作者:Smith JL, et al. (2021)*

*摘要*:通过靶向C1QTNF6的人源化抗体干预肥胖小鼠模型,证明其可减少脂肪组织巨噬细胞浸润,改善胰岛素抵抗,提示C1QTNF6在代谢炎症中的关键角色。

3. **"Structural characterization of C1QTNF6 and its therapeutic antibody binding epitope"**

*作者:Wang R, et al. (2020)*

*摘要*:利用冷冻电镜解析了C1QTNF6蛋白的三维结构,鉴定出与其功能性抗体结合的表位区域,为基于结构的抗体药物设计提供依据。

(注:以上文献为虚构示例,实际研究需通过PubMed或Google Scholar检索真实文献。)

背景信息

The C1QTNF6 antibody targets the complement C1q/tumor necrosis factor-related protein 6 (C1QTNF6), a member of the CTRP family involved in metabolic regulation, inflammation, and immune response. C1QTNF6 is primarily secreted by adipose tissue and plays roles in glucose metabolism, insulin sensitivity, and energy homeostasis, with potential links to obesity, diabetes, and cardiovascular diseases. It also modulates osteogenic differentiation and bone remodeling, suggesting relevance in skeletal disorders. Antibodies against C1QTNF6 are utilized in research to study its expression patterns, interaction partners, and signaling pathways, particularly in metabolic and inflammatory contexts. Recent studies explore its dual role in cancer—acting as a tumor suppressor or promoter depending on the tissue type—highlighting its therapeutic or diagnostic potential. These antibodies enable detection via techniques like Western blot, ELISA, and immunohistochemistry, aiding mechanistic insights into C1QTNF6's physiological and pathological functions. However, its precise mechanisms remain under investigation, necessitating further validation of antibody specificity and functional studies.

客户数据及评论

折叠内容

大包装询价

×