关键信息
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基因名
CCNK
- 应用
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别名
/
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种属
Human
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表达系统
Baculovirus
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标签
N- His
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O75909
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表达区间
1-354aa
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分子量
42.9 kDa
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CCNK (cyclin C-related kinase) is a member of the cyclin-dependent kinase (CDK) family, which plays a crucial role in cell cycle regulation and transcription. Recent research highlights the importance of CCNK in various cellular processes, including its potential involvement in oncogenesis. The protein exhibits unique interactions with cyclins and substrate proteins, suggesting a complex regulatory mechanism in cell proliferation and differentiation. Studies have shown that alterations in CCNK expression levels can lead to abnormal cell cycle progression and are associated with certain cancers. Consequently, the investigation of CCNK as a therapeutic target has garnered significant interest. Researchers are exploring the structural and functional aspects of CCNK to develop specific inhibitors that could modulate its activity, providing a possible avenue for cancer treatment. Furthermore, the recombinant expression of CCNK allows for detailed characterization of its biochemical properties and interactions within the cell, ultimately contributing to a better understanding of its role in cancer biology. This background sets the stage for future studies aimed at elucidating the precise functions of CCNK and its potential as a biomarker or therapeutic target in malignancies.
