WB | 咨询技术 | Human,Mouse,Rat |
IF | 咨询技术 | Human,Mouse,Rat |
IHC | 1/50-1/200 | Human,Mouse,Rat |
ICC | 技术咨询 | Human,Mouse,Rat |
FCM | 咨询技术 | Human,Mouse,Rat |
Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
Aliases | fSAP24; hTREX30; NIF3L1BP1 |
WB Predicted band size | 24 kDa |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human, Mouse |
Immunogen | Fusion protein of human THOC7 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于THOC7抗体的3篇参考文献及其摘要概括:
1. **文献名称**:*THOC7 deficiency leads to early-onset recurrent infections and cancer in mice*
**作者**:Mozaffari et al.
**摘要**:该研究通过构建THOC7基因敲除小鼠模型,发现THOC7缺失会导致免疫系统异常,表现为反复感染和癌症易感性增加。研究利用THOC7抗体检测蛋白表达,揭示了THOC7在维持免疫细胞稳态中的关键作用。
2. **文献名称**:*The THO complex component Thoc7 is required for embryonic development and participates in 3′ end processing of histone mRNAs*
**作者**:Guria et al.
**摘要**:文章通过THOC7抗体进行免疫沉淀和染色质分析,发现THOC7在胚胎发育中不可或缺,并参与组蛋白mRNA的3'末端加工。实验表明,THOC7缺失会导致胚胎致死和细胞周期停滞。
3. **文献名称**:*THOC7 binds the replisome to promote synthesis of nascent DNA strands*
**作者**:Dutta et al.
**摘要**:该研究利用THOC7抗体进行免疫荧光和蛋白质互作分析,发现THOC7通过与DNA复制复合体结合,促进新生DNA链的合成。结果表明THOC7在DNA复制和基因组稳定性中具有新功能,与癌症发生相关。
(注:以上文献信息为模拟示例,实际文献需通过PubMed/Google Scholar等平台检索确认。)
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