| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/40-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | 39K2; 39K3 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Fusion protein of human STAU2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是3篇与STAU2抗体相关的文献摘要(文献信息为虚构示例，仅供格式参考)：
1. **文献名称**：*Staufen2介导的mRNA转运在神经元突触可塑性中的作用*
**作者**：Li X, Wang Y, et al.
**摘要**：本研究利用STAU2特异性抗体，通过免疫共沉淀和RNA测序技术，揭示了STAU2蛋白在神经元树突中调控特定mRNA的定位，进而影响突触可塑性及学习记忆功能的分子机制。
2. **文献名称**：*STAU2在结直肠癌中的异常表达及其临床意义*
**作者**：Chen J, Zhang R, et al.
**摘要**：通过免疫组化实验(使用STAU2单克隆抗体)，发现STAU2在结直肠癌组织中高表达，且与肿瘤转移和患者预后不良显著相关，提示其作为潜在生物标志物的可能性。
3. **文献名称**：*STAU2与TDP-43相互作用在神经退行性疾病中的功能研究*
**作者**：Smith A, Brown K, et al.
**摘要**：研究采用STAU2抗体进行蛋白质印迹和免疫荧光共定位，证实STAU2与TDP-43在胞浆应激颗粒中相互作用，可能参与肌萎缩侧索硬化症(ALS)的病理过程。
(注：以上文献为示例性内容，实际引用需查询真实数据库如PubMed或Google Scholar。)
The Staufen homolog 2 (STAU2) antibody is a tool used to detect and study the STAU2 protein, a double-stranded RNA-binding protein involved in post-transcriptional gene regulation. STAU2. part of the Staufen family (alongside STAU1), plays roles in mRNA transport, localization, and stability, particularly in neuronal cells, where it supports synaptic plasticity, dendritic development, and learning. It interacts with various RNAs and proteins to regulate translation in a spatiotemporal manner, influencing processes like neurogenesis and cell differentiation.
STAU2 antibodies are widely employed in techniques such as Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to analyze protein expression, subcellular distribution, and interactions. Research highlights its relevance in neurodevelopmental disorders, cancer (e.g., glioblastoma, breast cancer), and neurodegenerative diseases, where dysregulated STAU2 expression correlates with pathological mechanisms. Commercial STAU2 antibodies are typically validated for specificity, often targeting conserved regions like its RNA-binding domains. However, users must verify cross-reactivity, especially with STAU1. due to structural similarities. Overall, STAU2 antibodies are critical for unraveling its biological functions and therapeutic potential in disease contexts.
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