| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Aliases | MEF-2; MST156; myEF-2; MSTP156; HsT18564 |
| WB Predicted band size | 64 kDa |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | Fusion protein of human MYEF2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是假设性示例的3篇关于MYEF2抗体的参考文献(注：实际文献需通过学术数据库验证)：
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1. **文献名称**: *MYEF2 regulates skeletal muscle differentiation and its antibody application in myogenesis analysis*
**作者**: Chen L, et al.
**摘要**: 本研究开发了特异性识别MYEF2蛋白的单克隆抗体，并通过免疫印迹和免疫荧光验证其在成肌细胞分化过程中对MYEF2表达的动态调控作用，揭示MYEF2在肌管形成中的功能。
2. **文献名称**: *Characterization of a polyclonal antibody against MYEF2 for studying its role in neural development*
**作者**: Kumar S, et al.
**摘要**: 文章报道了一种兔源多克隆抗体的制备，用于检测小鼠中枢神经系统发育中MYEF2的时空表达模式，提示其与少突胶质细胞分化及髓鞘生成相关。
3. **文献名称**: *MYEF2 antibody reveals its oncogenic potential in glioblastoma progression*
**作者**: Wang Y, et al.
**摘要**: 通过抗体验证发现MYEF2在胶质母细胞瘤中高表达，其抗体用于组织芯片分析，证明MYEF2过表达与患者预后不良及肿瘤侵袭性相关。
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**建议**：实际文献可通过PubMed、Google Scholar等平台以“MYEF2 antibody”或“MYEF2 function”为关键词检索，并筛选抗体开发或应用类研究。若需具体文献协助，请提供更多背景信息。
MYEF2 (Myelin Expression Factor 2) antibody is a tool used to study the MYEF2 protein, a member of the myelin transcription factor family. MYEF2. also known as N-AXIN or myelin expression factor 2. plays a role in regulating gene expression during neural development, particularly in oligodendrocytes responsible for myelination in the central nervous system. It contains a zinc finger domain and interacts with DNA to modulate transcription of myelin-related genes, such as proteolipid protein (PLP) and myelin basic protein (MBP). Dysregulation of MYEF2 has been implicated in demyelinating disorders like multiple sclerosis and leukodystrophies.
The MYEF2 antibody is commonly used in neuroscience research to investigate myelination mechanisms, oligodendrocyte differentiation, and neural repair processes. It enables detection of MYEF2 protein expression via techniques like Western blotting, immunohistochemistry, and immunofluorescence. Studies also utilize this antibody to explore MYEF2's interactions with other regulatory proteins, such as β-catenin in the Wnt signaling pathway, which influences myelination and axonal guidance. Commercial MYEF2 antibodies are typically raised in rabbits or mice, validated for specificity in human, mouse, or rat tissues. Recent research highlights its potential role in brain tumors and neurodegenerative diseases, underscoring its relevance in both basic and translational neuroscience.
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