Rabbit Polyclonal RTP4 Antibody

The RTP4 (Receptor Transporting Protein 4) antibody is a tool used to study the RTP4 protein, a member of the RTP family that facilitates the trafficking of olfactory and taste receptors to the cell membrane. RTP4. along with RTP1 and RTP2. acts as a chaperone, aiding in the functional expression of G protein-coupled receptors (GPCRs), particularly odorant receptors, by promoting their endoplasmic reticulum-to-plasma membrane transport. This protein is expressed in olfactory sensory neurons and other tissues, with roles extending beyond chemosensation, including potential involvement in cancer progression and immune regulation. The RTP4 antibody enables detection and localization of RTP4 in experimental models (e.g., Western blot, immunohistochemistry), helping researchers investigate its biological functions and interactions. Recent studies highlight RTP4's association with neuroendocrine tumors, viral infections, and inflammatory responses, suggesting its utility as a biomarker or therapeutic target. Commercial RTP4 antibodies are typically developed in rabbit or mouse hosts, validated for specificity against human, mouse, or rat homologs. Its study contributes to understanding receptor maturation mechanisms and disease pathways linked to GPCR dysregulation.