| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/50-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/3000-1/10000 | Human,Mouse,Rat |
| Aliases | ODZ3; TNM3; Ten-m3 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human TENM3 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
+ +
以下是关于TENM3抗体的3篇虚构参考文献示例(仅供参考，实际文献需通过学术数据库查询)：
---
1. **文献名称**：*Teneurin-3 (TENM3) Antibody Validation and Expression in Mouse Brain Development*
**作者**：Smith A, et al.
**摘要**：本研究开发并验证了一种特异性识别TENM3蛋白的多克隆抗体，通过免疫印迹和免疫组化证实其在小鼠大脑皮层和海马中的动态表达模式，提示TENM3在神经元迁移和突触形成中的潜在作用。
---
2. **文献名称**：*TENM3 as a Biomarker in Glioblastoma: Antibody-Based Detection and Clinical Correlations*
**作者**：Chen L, et al.
**摘要**：利用商业化TENM3抗体进行免疫组织化学分析，发现TENM3在胶质母细胞瘤中高表达，且与患者生存率负相关，提示其可能作为治疗靶点或预后标志物。
---
3. **文献名称**：*Functional Analysis of TENM3 in Retinal Circuitry Using CRISPR/Cas9 and Antibody Labeling*
**作者**：Garcia R, et al.
**摘要**：通过CRISPR技术敲除斑马鱼TENM3基因，结合特异性抗体标记，揭示TENM3对视网膜双极细胞轴突导向的关键调控作用，为神经回路发育机制提供新证据。
---
如需真实文献，建议在PubMed或Google Scholar中搜索关键词“TENM3 antibody”、“Teneurin-3 antibody”或“ODZ3 antibody”获取最新研究。
TENM3 (Teneurin transmembrane protein 3), also known as Odz3. is a member of the teneurin family of highly conserved type II transmembrane proteins, which includes four paralogs (TENM1-4) in vertebrates. These proteins are characterized by large extracellular regions containing multiple epidermal growth factor (EGF)-like domains and a unique YD-shell motif, followed by transmembrane and intracellular domains. TENM3 is prominently expressed in the nervous system and plays critical roles in embryonic development, particularly in neural circuit formation, axon guidance, and synaptic organization. It mediates cell-cell adhesion and signaling, influencing topographic mapping of neuronal connections in the visual and olfactory systems.
Antibodies targeting TENM3 are essential tools for investigating its spatial-temporal expression patterns, molecular interactions, and functional mechanisms. They are widely used in techniques like immunohistochemistry, Western blotting, and immunofluorescence to visualize TENM3 distribution in tissues or cultured cells. Studies using TENM3 antibodies have contributed to understanding its involvement in neurodevelopmental disorders and potential links to cancers, where aberrant expression has been observed. However, research on TENM3 remains less extensive compared to other teneurins, emphasizing the need for well-validated antibodies to explore its multifaceted roles in health and disease.
×
