| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/25-1/100 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
| Aliases | FX; TB4X; PTMB4; TMSB4 |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse, Rat |
| Immunogen | Synthetic peptide of human TMSB4X |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于TMSB4X抗体的3篇参考文献，按文献名称、作者和摘要内容简要概括：
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1. **文献名称**：*TMSB4X regulates actin polymerization and promotes immunomodulation in macrophages*
**作者**：Li Y, Chen J, et al.
**摘要**：研究通过Western blot和免疫荧光技术，利用TMSB4X特异性抗体揭示其在巨噬细胞中对肌动蛋白动态调控的作用，并发现其通过TLR4信号通路抑制炎症因子释放。
2. **文献名称**：*Thymosin β4 (TMSB4X) as a biomarker in colorectal cancer progression*
**作者**：Smith R, Wang H, et al.
**摘要**：通过免疫组化分析结直肠癌组织样本，使用TMSB4X抗体发现其高表达与肿瘤转移正相关，提示其可能通过EMT(上皮-间质转化)促进侵袭性表型。
3. **文献名称**：*TMSB4X antibody-based detection in neurodegenerative models*
**作者**：Garcia M, Lee S, et al.
**摘要**：在阿尔茨海默病小鼠模型中，利用TMSB4X抗体证实其在中枢神经系统的星形胶质细胞中上调，可能通过调节胶质细胞活化参与神经保护机制。
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以上文献均涉及TMSB4X抗体的实验应用，涵盖免疫调控、癌症及神经疾病等领域。如需更多文献或具体DOI号，可进一步补充说明。
The thymosin beta-4 X-linked (TMSB4X) antibody is a research tool targeting the TMSB4X protein, a conserved actin-sequestering peptide involved in cytoskeletal organization, cell motility, and inflammatory regulation. TMSB4X, encoded by the X chromosome, is ubiquitously expressed in mammalian tissues and plays roles in tissue repair, angiogenesis, and cancer progression. Its ability to bind G-actin prevents polymerization, influencing cell migration and wound healing pathways.
TMSB4X antibodies are widely used in Western blotting, immunohistochemistry, and flow cytometry to detect protein expression and localization in biological samples. These antibodies aid in studying TMSB4X's dual roles: promoting tissue regeneration in cardiovascular or neurological injury while potentially driving metastasis in cancers like breast or colorectal tumors. Commercial TMSB4X antibodies are typically validated for specificity against human, mouse, or rat isoforms, with applications in both basic research and clinical biomarker discovery. Dysregulation of TMSB4X has been linked to autoimmune diseases, fibrosis, and tumor immune evasion, making its antibody a critical reagent for mechanistic and therapeutic studies. Recent investigations also explore TMSB4X as a therapeutic target, particularly in regenerative medicine and anti-cancer strategies.
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