| WB | 咨询技术 | Human,Mouse,Rat |
| IF | 咨询技术 | Human,Mouse,Rat |
| IHC | 1/40-1/200 | Human,Mouse,Rat |
| ICC | 技术咨询 | Human,Mouse,Rat |
| FCM | 咨询技术 | Human,Mouse,Rat |
| Elisa | 1/5000-1/10000 | Human,Mouse,Rat |
| Host/Isotype | Rabbit IgG |
| Antibody Type | Primary antibody |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | Synthetic peptide of human YEATS2 |
| Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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以下是关于YEATS2抗体的3篇参考文献示例(注：以下内容为虚构，仅作格式参考，实际文献需通过学术数据库检索获取)：
1. **文献名称**：*"YEATS2 Antibody Validation and Its Role in Chromatin Remodeling Complexes"*
**作者**：Smith A, et al.
**摘要**：本研究验证了一种高特异性YEATS2抗体的应用，通过免疫沉淀和Western blot证实其在识别内源性YEATS2蛋白中的可靠性，并揭示YEATS2作为染色质重塑复合体成员在调控基因转录中的作用。
2. **文献名称**：*"Targeting YEATS2 in Cancer: Antibody-Based Detection and Functional Analysis"*
**作者**：Lee J, et al.
**摘要**：利用YEATS2特异性抗体，研究者发现YEATS2在多种癌细胞系中高表达，并通过免疫组化证明其与肿瘤分级相关。功能实验表明，敲低YEATS2可抑制癌细胞增殖。
3. **文献名称**：*"Structural and Functional Characterization of the YEATS2 Domain Using Custom Antibodies"*
**作者**：Garcia R, et al.
**摘要**：该研究开发了靶向YEATS2结构域的多克隆抗体，结合冷冻电镜技术解析了YEATS2与组蛋白修饰的结合模式，阐明其在表观遗传调控中的分子机制。
如需真实文献，建议通过PubMed或Google Scholar搜索“YEATS2 antibody”或“YEATS2 protein detection”获取近期研究。
The YEATS2 antibody is a research tool designed to detect and study the YEATS domain-containing protein 2. a key component of the ATAC (Ada-Two-A-containing) and NuA4/TIP60 histone acetyltransferase complexes. YEATS2 plays a critical role in epigenetic regulation by recognizing acylated histones (e.g., acetylated or crotonylated lysine residues) and facilitating chromatin remodeling, which influences gene transcription, DNA repair, and cell cycle progression. It is implicated in developmental processes and diseases, including cancers and neurodevelopmental disorders.
YEATS2 antibodies are typically developed in host species like rabbits or mice using immunogenic peptides or recombinant protein fragments. These antibodies are validated for applications such as Western blotting, immunoprecipitation, immunofluorescence, and ChIP-seq. Researchers use them to explore YEATS2's molecular interactions, expression patterns, and functional roles in cellular pathways. Specificity is often confirmed via knockout (KO) controls or siRNA knockdown.
As dysregulation of YEATS2 is linked to oncogenesis (e.g., leukemia, breast cancer) and chromatin-related disorders, its antibody serves as a vital reagent for dissecting epigenetic mechanisms and evaluating therapeutic targets. Commercial variants vary in clonality, conjugation, and host compatibility, tailored for diverse experimental needs.
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