关键信息
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基因名
CHUK
- 应用
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别名
IKKA; TCF16
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种属
Human
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表达系统
Baculovirus
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标签
His;GST
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纯度
Greater than 90% as determined by SDS-PAGE.
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蛋白编号
O15111
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表达区间
E2-E745
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蛋白长度
Full Length
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内毒素
< 1.0 EU per μg protein as determined by the LAL method.
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性状
Freeze-dried powder
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缓冲液
PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
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复溶方法
Reconstitute in ddH2O to a concentration of 0.1-0.5 mg/mL. Do not vortex.
- 个性化定制
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稳定性测试
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37℃ for 48h, and no obvious degradation and precipitation were observed. The loss rate isless than 8% within the expiration date under appropriate storage condition.
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保存条件 & 期限
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
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运输条件
In general, recombinant proteins are supplied as lyophilized powder and shipped at ambient temperature. For bulk packages, the proteins are provided as frozen liquid and shipped with blue ice, unless otherwise requested by the customer.
质检流程
相关产品
背景信息
CHUK, also known as IKK-alpha, is a critical component of the inhibitor of kappa B kinase (IKK) complex, which plays a pivotal role in the regulation of the NF-kB signaling pathway. This pathway is essential for various cellular processes, including immune responses, inflammation, and cell survival. Dysregulation of NF-kB signaling has been implicated in numerous diseases, including cancer, autoimmune disorders, and chronic inflammatory conditions. Therefore, CHUK and its associated pathways have garnered significant attention in biomedical research. The reconstitution and characterization of CHUK recombinant proteins allow for in-depth studies of its biochemical properties and functional dynamics. By expressing CHUK in heterologous systems, researchers can elucidate its role in the NF-kB signaling cascade and explore its interactions with other proteins and cellular mechanisms. Such studies have the potential to uncover novel therapeutic targets and strategies for diseases where NF-kB is dysregulated. Consequently, the research on CHUK recombinant proteins is not only fundamental for understanding cell signaling but also provides insights into the development of innovative treatments for complex diseases.
